As a Clinician-Scientist, I have a strong interest in conducting translational research that bridges our understanding on the neurobiology of psychiatric illnesses with the clinical applications of this knowledge. I am particularly interested in applying this strategy to severe psychiatric disorders such as refractory psychosis and treatment resistant depression. My clinical practice is actively focused in those most severely afflicted by such conditions, and my research interests are directed at finding novel therapeutic interventions within Non-Invasive Neurostimulation Therapies (NINETs) that can help mitigate the suffering of those with severe and refractory forms of psychosis and depression, including pediatric populations. I strongly believe that understanding NINETs’ mechanism(s) of action is a critical step towards translating this knowledge to clinical practice. More important, translating that knowledge to clinical practice will have a direct, immediate, and positive impact on the life’s of those who struggle and suffer the most devastating forms of mental illness and their families.
Dynamic networks of psychotic symptoms in adults living in precarious housing or homelessness
Andrea A. Jones and Kristina M. Gicas and Sara Mostafavi and Melissa L. Woodward and Olga Leonova and Fidel Vila-Rodriguez and Ric M. Procyshyn and Alex Cheng and Tari Buchanan and Donna J. Lang and G. William MacEwan and William J. Panenka and Alasdair M. Barr and Allen E. Thornton and William G. Honer
SS-Detect: Development and Validation of a New Strategy for Source-Based Morphometry in Multiscanner Studies
Journal of Neuroimaging
Ruiyang Ge and Shiqing Ding and Tyler Keeling and William G. Honer and Sophia Frangou and Fidel Vila-Rodriguez
Effect of repetitive transcranial magnetic stimulation on anxiety symptoms in patients with major depression: An analysis from the THREE-D trial
Depression and Anxiety
Alisson P. Trevizol and Jonathan Downar and Fidel Vila-Rodriguez and Gerasimos Konstantinou and Zafiris J. Daskalakis and Daniel M. Blumberger
The role of low-frequency repetitive transcranial magnetic stimulation in major depression: A call to increase the evidence base
Jean-Philippe Miron and Jack Sheen and Farrokh Mansouri and Daniel M. Blumberger and Zafiris J. Daskalakis and Fidel Vila-Rodriguez and Jonathan Downar
Associations of substance use, psychosis, and mortality among people living in precarious housing or homelessness: A longitudinal, community-based study in Vancouver, Canada
Andrea A. Jones and Kristina M. Gicas and Sam Seyedin and Taylor S. Willi and Olga Leonova and Fidel Vila-Rodriguez and Ric M. Procyshyn and Geoffrey N. Smith and Toby A. Schmitt and A. Talia Vertinsky and Tari Buchanan and Alex Rauscher and Donna J. Lang and G. William MacEwan and Viviane D. Lima and Julio S. G. Montaner and William J. Panenka and Alasdair M. Barr and Allen E. Thornton and William G. Honer
Impact of cannabis mass gathering events on mental health and health service utilization
Patrick Lombardo and Andrew Lim and Andrea A. Jones and Daniel Vigo and William G. Honer and Jennifer Duff and G. William MacEwan and Fidel Vila-Rodriguez
Evaluation of the effects of rTMS on self-reported quality of life and disability in treatment-resistant depression: A THREE-D study.
Journal of affective disorders
Towards Competency-Based Medical Education in Neurostimulation.
Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry
Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness.
The American journal of psychiatry
Cardiovascular differences between sham and active iTBS related to treatment response in MDD
Tabitha A. Iseger and Martijn Arns and Jonathan Downar and Daniel M. Blumberger and Zafiris J. Daskalakis and Fidel Vila-Rodriguez
Use of Machine Learning for Predicting Escitalopram Treatment Outcome From Electroencephalography Recordings in Adult Patients With Depression.
JAMA network open
Functional connectivity of the anterior cingulate cortex predicts treatment outcome for rTMS in treatment-resistant depression at 3-month follow-up
Ruiyang Ge and Jonathan Downar and Daniel M. Blumberger and Zafiris J. Daskalakis and Fidel Vila-Rodriguez
International Consortium on the Genetics of Electroconvulsive Therapy and Severe Depressive Disorders (Gen-ECT-ic).
European archives of psychiatry and clinical neuroscience
Impact of prior treatment on remission with intermittent theta burst versus high-frequency repetitive transcranial magnetic stimulation in treatment resistant depression
Jonathan H. Hsu and Jonathan Downar and Fidel Vila-Rodriguez and Zafiris J. Daskalakis and Daniel M. Blumberger
Effects of Ketamine Anesthesia on Efficacy, Tolerability, Seizure Response, and Neurocognitive Outcomes in Electroconvulsive Therapy: A Comprehensive Meta-analysis of Double-Blind Randomized Controlled Trials.
The journal of ECT
Interleaved Transcranial Magnetic Stimulation and Functional Magnetic Resonance Imaging: A Translational Tool
Clinical Pharmacology & Therapeutics
Fidel Vila-Rodriguez and Ruiyang Ge and David Long
Longer Repetition Time Proton MR Spectroscopy Shows Increasing Hippocampal and Parahippocampal Metabolite Concentrations with Aging
Journal of Neuroimaging
Leo Sporn and Erin L. MacMillan and Ruiyang Ge and Kyle Greenway and Fidel Vila-Rodriguez and Cornelia Laule
Implementation of intermittent theta burst stimulation compared to conventional repetitive transcranial magnetic stimulation in patients with treatment resistant depression: A cost analysis.
A comparison of regional brain volumes and white matter connectivity in subjects with stimulant induced psychosis versus schizophrenia.
Volumes of the Hippocampal Formation Differentiate Component Processes of Memory in a Community Sample of Homeless and Marginally Housed Persons.
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists
Lifesaving Electroconvulsive Therapy for a Child With Autism Spectrum Disorder, Severe Self-Injurious Behavior, and Neuroleptic Malignant Syndrome.
The journal of ECT
Functional disconnectivity of the hippocampal network and neural correlates of memory impairment in treatment-resistant depression.
Journal of affective disorders
Symptomatic and Functional Outcomes and Early Prediction of Response to Escitalopram Monotherapy and Sequential Adjunctive Aripiprazole Therapy in Patients With Major Depressive Disorder: A CAN-BIND-1 Report.
The Journal of clinical psychiatry
Structural network integrity of the central executive network is associated with the therapeutic effect of rTMS in treatment resistant depression.
Progress in neuro-psychopharmacology & biological psychiatry
Non-linear Entropy Analysis in EEG to Predict Treatment Response to Repetitive Transcranial Magnetic Stimulation in Depression.
Frontiers in Pharmacology
Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size.
Clinical and functional characteristics of young adults living in single room occupancy housing: preliminary findings from a 10-year longitudinal study.
Canadian journal of public health = Revue canadienne de sante publique
Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial.
Lancet (London, England)
Verbal memory improvement in first-episode psychosis APOE-ε4 carriers: a pleiotropic effect?
Neuropsychiatric Disease and Treatment
Fidel Vila-Rodriguez and Donna Lang and Heather Baitz and Kristina Gicas and Allen Thornton and Thomas Ehmann and Geoff N. Smith and Alasdair Barr and Ivan J. Torres and Lili Kopala and G. William MacEwan and Daniel Müller and James Kennedy and William Honer
Abnormal Functional Connectivity of Frontopolar Subregions in Treatment-Nonresponsive Major Depressive Disorder.
Biological psychiatry. Cognitive neuroscience and neuroimaging
Standardization of electroencephalography for multi-site, multi-platform and multi-investigator studies: insights from the canadian biomarker integration network in depression.
A sparse representation-based method for parcellation of the resting brain and its application to treatment-resistant major depressive disorder.
Journal of neuroscience methods
Structural brain markers are differentially associated with neurocognitive profiles in socially marginalized people with multimorbid illness.
Kristina M. Gicas and Chantelle J. Giesbrecht and William J. Panenka and Donna J. Lang and Geoffrey N. Smith and Fidel Vila-Rodriguez and Olga Leonova and Andrea A. Jones and Alasdair M. Barr and Ric M. Procyshyn and Tari Buchanan and G. William MacEwan and Wayne Su and A. Talia Vertinsky and Alexander Rauscher and William G. Honer and Allen E. Thornton
Abnormal functional connectivity within resting-state networks is related to rTMS-based therapy effects of treatment resistant depression: A pilot study
Journal of Affective Disorders
Characterization of white matter integrity deficits in cocaine-dependent individuals with substance-induced psychosis compared with non-psychotic cocaine users
Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: Section 4. Neurostimulation treatments
Canadian Journal of Psychiatry
The positive and negative syndrome scale (PANSS): A three-factor model of psychopathology in marginally housed persons with substance dependence and psychiatric illness
Unilateral and bilateral MRI-targeted repetitive transcranial magnetic stimulation for treatmentresistant depression: A randomized controlled study
Journal of Psychiatry and Neuroscience
Factors affecting severity of positive and negative symptoms of psychosis in a polysubstance using population with psychostimulant dependence
Subcortical grey matter alterations in cocaine dependent individuals with substance-induced psychosis compared to non-psychotic cocaine users
A Tetra-Primer Amplification Refractory System Technique for the Cost-Effective and Novel Genotyping of Eight Single-Nucleotide Polymorphisms of the Catechol-O-Methyltransferase Gene
Genetic Testing and Molecular Biomarkers
Discovering biomarkers for antidepressant response: Protocol from the Canadian biomarker integration network in depression (CAN-BIND) and clinical characteristics of the first patient cohort
Dimenhydrinate use disorder with chronic psychosis
Journal of Clinical Psychopharmacology
Response trajectories to clozapine in a secondary analysis of pivotal trials support using treatment response to subtype schizophrenia
Canadian journal of psychiatry. Revue canadienne de psychiatrie
NEUROBIOLOGICAL PREDICTORS of RESPONSE to DORSOLATERAL PREFRONTAL CORTEX REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION in DEPRESSION: A SYSTEMATIC REVIEW
Depression and Anxiety
Neurobiological mechanisms of repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex in depression: A systematic review
Development of a cost-efficient novel method for rapid, concurrent genotyping of five common single nucleotide polymorphisms of the brain derived neurotrophic factor (BDNF) gene by tetra-primer amplification refractory mutation system
International Journal of Methods in Psychiatric Research
White matter deficits assessed by diffusion tensor imaging and cognitive dysfunction in psychostimulant users with comorbid human immunodeficiency virus infection Psychiatry
BMC Research Notes
Neuroleptic malignant syndrome: A review from a clinically oriented perspective
Neurocognitive profiles of marginally housed persons with comorbid substance dependence, viral infection, and psychiatric illness
Journal of Clinical and Experimental Neuropsychology
Normal Pressure Hydrocephalus: Etiology, Diagnosis, Treatment, and Putative Nutritional and Lifestyle Risk Factors
Diet and Nutrition in Dementia and Cognitive Decline
Repetitive transcranial magnetic stimulation in depression: A changing landscape
One year prevalence of mental disorders comorbidity and associated socio-demographic risk factors in the general population of Spain. Results of the ESEMeD-Spain study | Prevalencia-año de la comorbilidad de los trastornos mentales y factores de riesgo sociodemográficos asociados en la población general de España. Resultados del estudio ESEMeD-España.
Actas españolas de psiquiatría