Matthias Görges

PhD, MSc

Investigator, BC Children's Hospital, Co-Lead, Digital Health and Data Analytics Super Hub, BC Children's Hospital

As part of an inter-disciplinary team of engineers, computer scientists, and health care providers, I am involved in a wide range of projects focusing on the development and application of new technology, primarily in the pediatric anesthesia and intensive care setting. My main goal is to extract clinically-useful information from vital signs and other clinical data, and to transform these data into information for better, more timely, and more efficient decision-making by clinicians.

Academic Affiliations

  • Associate Professor, , Department of Anesthesiology, Pharmacology & Therapeutics, Faculty of Medicine, University of British Columbia
  • Research Theme: Evidence to Innovation
  • Research Group(s): Clinical Practice, Outcomes and Innovation; Clinical and Community Data, Analytics and Informatics; Global Health and Innovations

Contact Information

Location

950 West 28th Avenue, V3-324, Vancouver, British Columbia, Canada, V5Z 4H4

Impact of Digitally Enabled Peer Support Interventions on Diabetes Distress and Depressive Symptoms in People Living with Type 1 Diabetes: A Systematic Review

Current Diabetes Reports

Titilola I. Yakubu and Samantha Pawer and Nicholas C. West and Tricia S. Tang and Matthias Grges

DOI: 10.1007/s11892-024-01560-4

12 / 2025

A standardized set of metrics to assess the quality of anesthesia, perioperative care, and acute pain management in Canada: a multidisciplinary modified Delphi study

Canadian Journal of Anesthesia/Journal canadien d'anesthsie

Janny Xue Chen Ke and Mindy A. Smith and Kathryn Sparrow and Nicholas West and May-Sann Yee and Kang Mu Yoo and Louise Y. Sun and W. Scott Beattie and Matthias Grges and for the Canadian Perioperative Anesthesia Clinical Trials (PACT) Group

DOI: 10.1007/s12630-025-02951-1

05 / 2025

Identifying Contextual Factors That Shape Cybersecurity Risk Perception for Assisted Living and Health Care Technologies and Wearables: Mixed Methods Study

Journal of Medical Internet Research

Alvhild Skjelvik and Nicholas West and Matthias Grges

DOI: 10.2196/64388

03 / 2025

Exploring the Needs and Preferences of Users and Parents to Design a Mobile App to Deliver Mental Health Peer Support to Adolescents With Type 1 Diabetes: Qualitative Study

JMIR Diabetes

Titilola I Yakubu and Poonamdeep Jhajj and Samantha Pawer and Nicholas C West and Shazhan Amed and Tricia S Tang and Matthias Grges

DOI: 10.2196/64267

01 / 2025

Development and internal validation of time-to-event risk prediction models for major medical complications within 30 days after elective colectomy

PLOS ONE

Janny X. C. Ke and Tim T. H. Jen and Sihaoyu Gao and Long Ngo and Lang Wu and Alana M. Flexman and Stephan K. W. Schwarz and Carl J. Brown and Matthias Grges

DOI: 10.1371/journal.pone.0314526

12 / 2024

Using peri-operative patient- and parent-reported experience and outcome measures to identify paediatric postsurgical recovery trajectories: an observational cohort study

Anaesthesia

Samantha Pang and Nicholas West and Haoyu Zhao and Jessica Luo and Neil K. Chadha and Lynnie R. Correll and Heng Gan and Matthias Grges

DOI: 10.1111/anae.70180

02 / 2026

Pharmacodynamic Safety Endpoints for Propofol Anesthesia in Children by Age and Sex: A Multicohort Observational Study

Pediatric Anesthesia

Lindy Moxham and Aanisah Golam and Nicholas C. West and Matthias Grges and Simon D. Whyte

DOI: 10.1111/pan.70031

12 / 2025

Caregiver experiences of an integrative patient-centered digital health application for pediatric type 1 diabetes care: Findings from a pilot clinical trial

PLOS Digital Health

Shazhan Amed and Haleh Ayatollahi and Susan Pinkney and Fatema S. Abdulhussein and Anila Virani and Carlie Zachariuk and Sukhpreet K. Tamana and Shruti Muralidharan and Matthias Grges and Bonnie Barrett and Tibor van Rooij and Elizabeth M. Borycki and Andre Kushniruk and Holly Longstaff and Alice Virani and Wyeth W. Wasserman

DOI: 10.1371/journal.pdig.0000861

10 / 2025

Developing Requirements for a Standardized System to Return Individual Research Results Back to Study Participants: Narrative Review

Interactive Journal of Medical Research

Rosalyn Leigh Carr and Vita Chan and Nicholas C West and Matthias Grges

DOI: 10.2196/65606

08 / 2025

The Effectiveness of Bubble-Blowing as a Distraction Technique During Pediatric Intravenous Cannulation: A Randomized Controlled Trial

Pediatric Anesthesia

McKenna Postles and Nicholas West and Lindy Moxham and Jenna Ramji and Jade Palm and Christa Morrison and Matthias Grges and James Chen

DOI: 10.1111/pan.15138

08 / 2025

Perioperative Intravenous Lidocaine Infusion Therapy as an Adjunct to Multimodal Analgesia for Adolescent Idiopathic Scoliosis Surgical Correction: A Double-Blind Randomized Controlled Trial

Pediatric Anesthesia

Jessica Luo and Nicholas West and Samantha Pang and Aanisah Golam and Erin Adams and Matthias Grges and Roxane R. Carr and Firoz Miyanji and Gillian R. Lauder

DOI: 10.1111/pan.15124

07 / 2025

Anesthetic-Sparing Effect of Dexmedetomidine During Total Intravenous Anesthesia for Children Undergoing Dental Surgery: A Randomized Controlled Trial"In Reply

Pediatric Anesthesia

Victor C. L. Lee and Randa Ridgway and Nicholas C. West and Matthias Grges and Simon D. Whyte

DOI: 10.1111/pan.15109

06 / 2025

Metrics to assess the quality of anesthesia, perioperative care, and acute pain management in Canada: a scoping review

Canadian Journal of Anesthesia/Journal canadien d'anesthsie

Janny X. C. Ke and Kathryn Sparrow and Mindy A. Smith and Kang Mu Yoo and May-Sann Yee and Louise Y. Sun and W. Scott Beattie and Edlyn Lim and Matthias Grges

DOI: 10.1007/s12630-025-02943-1

05 / 2025

Evaluating a mental health support mobile app for adults with type 1 diabetes living in rural and remote communities: The REACHOUT pilot study

Diabetic Medicine

Tricia S. Tang and Gerri Klein and Matthias Grges and Annie Yip and Lawrence Fisher and William H. Polonsky and Danielle Hessler and Deanne Taylor

DOI: 10.1111/dme.15451

03 / 2025

Integrative Medicine Modalities for Adolescent Patients Undergoing Minimally Invasive Repair of Pectus Excavatum: A Scoping Review

Journal of Integrative and Complementary Medicine

Ramji, J. and Pawliuk, C. and Rowe, J. and Baird, R. and Ridgway, R. and G{\"o}rges, M. and Correll, L.R.

DOI: 10.1177/27683605251366993

Ictal Asystole During ECT

Journal of ECT

Pozdnikoff, C. and Johnston, J. and Najafi, F. and Gregory, E. and Hamidizadeh, R. and Hrazdil, C. and G{\"o}rges, M. and Vila-Rodriguez, F.

DOI: 10.1097/YCT.0000000000001178

Developing the Standardized Workload Assessment Metric for Pediatric Emergency Departments: Initial Steps Using a Modified Delphi Method

Pediatric Emergency Care

Rose, J. and Chong, A. and Mckinley, K. and Meckler, G. and Van Rooij, T. and G{\"o}rges, M. and Principi, T. and Gravel, J. and Singh, D. and Hurley, K. and Wright, B. and Turner, T. and Mater, A. and Burstein, B. and Doan, Q.

DOI: 10.1097/PEC.0000000000003353

Parental Perspectives on Pediatric Surgical Recovery: Narrative Analysis of Free-Text Comments From a Postoperative Survey

JMIR Perioperative Medicine

Jessica Luo and Nicholas C West and Samantha Pang and Julie M. Robillard and Patricia Page and Neil K. Chadha and Heng Gan and Lynnie Correll and Randa Ridgway and Natasha Broemling and Matthias Grges and Pediatric Pain Prediction Collaboration

DOI: 10.2196/65198

12 / 2024

Anesthetic-sparing effect of dexmedetomidine during total intravenous anesthesia for children undergoing dental surgery: A randomized controlled trial

Pediatric Anesthesia

Victor C. L. Lee and Randa Ridgway and Nicholas C. West and Matthias Grges and Simon D. Whyte

DOI: 10.1111/pan.14987

12 / 2024

Caregiver and Youth Characteristics That Influence Trust in Digital Health Platforms in Pediatric Care: Mixed Methods Study

Journal of Medical Internet Research

Eric Chow and Alice Virani and Susan Pinkney and Fatema S Abdulhussein and Tibor van Rooij and Matthias Grges and Wyeth Wasserman and Jeffrey Bone and Holly Longstaff and Shazhan Amed

DOI: 10.2196/53657

10 / 2024

Postsurgical Pain Risk Stratification to Enhance Pain Management Workflow in Adult Patients: Design, Implementation, and Pilot Evaluation

Jmir Perioperative Medicine

G{\"o}rges, M. and Sujan, J. and West, N.C. and Sreepada, R.S. and Wood, M.D. and Payne, B.A. and Shetty, S. and Gelinas, J.P. and Sutherland, A.M.

DOI: 10.2196/54926

Using Human-Centered Design and Cocreation to Create the Live 5-2-1-0 Mobile App to Promote Healthy Behaviors in Children: App Design and Development

JMIR Pediatrics and Parenting

Yau, K.W. and Tang, T.S. and Grges, M. and Pinkney, S. and Amed, S.

DOI: 10.2196/44792

Designing a Collaborative Patient-Centered Digital Health Platform for Pediatric Diabetes Care in British Columbia: Formative Needs Assessment by Caregivers of Children and Youths Living With Type 1 Diabetes and Health Care Providers

JMIR Pediatrics and Parenting

Abdulhussein, F.S. and Pinkney, S. and Grges, M. and van Rooij, T. and Amed, S.

DOI: 10.2196/46432

Enhanced recovery support for people with eating disorders during the COVID-19 pandemic: quality improvement using a web-based, stepped-care programme in Canada

BMJ Open Quality

Wood, M.D. and Smith, J.L. and Healey, H. and Grges, M. and Lokker, C.

DOI: 10.1136/bmjoq-2023-002366

Prediction of Blood Risk Score in Diabetes Using Deep Neural Networks

Journal of Clinical Medicine

Toledo-Marn, J.Q. and Ali, T. and van Rooij, T. and Grges, M. and Wasserman, W.W.

DOI: 10.3390/jcm12041695

Pediatric Delirium Educational Tool Development With Intensive Care Unit Clinicians and Caregivers in Canada: Focus Group Study

Jmir Pediatrics and Parenting

Wood, M. and Gandhi, K. and Chapman, A. and Skippen, P. and Krahn, G. and G{\"o}rges, M. and Stewart, S.E.

DOI: 10.2196/53120

Dashboard of Short-Term Postoperative Patient Outcomes for Anesthesiologists: Development and Preliminary Evaluation

JMIR Perioperative Medicine

Sreepada, R.S. and Chang, A.C. and West, N.C. and Sujan, J. and Lai, B. and Poznikoff, A.K. and Munk, R. and Froese, N.R. and Chen, J.C. and Grges, M.

DOI: 10.2196/47398

An Individualized Postoperative Pain Risk Communication Tool for Use in Pediatric Surgery: Co-Design and Usability Evaluation

JMIR Pediatrics and Parenting

Wood, M.D. and West, N.C. and Fokkens, C. and Chen, Y. and Loftsgard, K.C. and Cardinal, K. and Whyte, S.D. and Portales-Casamar, E. and Grges, M.

DOI: 10.2196/46785

Effectiveness of Mobile Apps in Promoting Healthy Behavior Changes and Preventing Obesity in Children: Systematic Review

JMIR Pediatrics and Parenting

Yau, K.W. and Tang, T.S. and Gorges, M. and Pinkney, S. and Kim, A.D. and Kalia, A. and Amed, S.

DOI: 10.2196/34967

Prediction Model Performance With Different Imputation Strategies: A Simulation Study Using a North American ICU Registry

Pediatric Critical Care Medicine

Steif, J. and Brant, R. and Sreepada, R.S. and West, N. and Murthy, S. and G{\"o}rges, M.

DOI: 10.1097/PCC.0000000000002835

Identification of Requirements for a Postoperative Pediatric Pain Risk Communication Tool: Focus Group Study With Clinicians and Family Members

JMIR Pediatrics and Parenting

Wood, M.D. and Correa, K. and Ding, P. and Sreepada, R. and Loftsgard, K.C. and Jordan, I. and West, N.C. and Whyte, S.D. and Portales-Casamar, E. and Grges, M.

DOI: 10.2196/37353

Blood pressure nomograms for children undergoing general anesthesia, stratified by age and anesthetic type, using data from aretrospective cohort at a tertiary pediatric center

Journal of Clinical Monitoring and Computing

Hillgruber, R.J. and Lutskov, P. and West, N.C. and Whyte, S. and G{\"o}rges, M.

DOI: 10.1007/s10877-022-00811-7

Has Virtual Care Arrived? A Survey of Rural Canadian Providers During the Early Stages of the COVID-19 Pandemic

Health Services Insights

Burton, L. and Rush, K.L. and Smith, M.A. and Grges, M. and Currie, L.M. and Davis, S. and Mattei, M. and Ellis, J.

DOI: 10.1177/11786329221096033

Empowering Patients Through Virtual Care Delivery: Qualitative Study With Micropractice Clinic Patients and Health Care Providers

JMIR Formative Research

Burton, L. and Rush, K.L. and Smith, M.A. and Davis, S. and Echeverria, P.R. and Hidalgo, L.S. and Grges, M.

DOI: 10.2196/32528

Association of dexmedetomidine with recovery room and hospital discharge times: A retrospective cohort analysis

Pediatric Anesthesia

Nicholas West and Matthias Grges and Andrew Poznikoff and Simon Whyte and Stephan Malherbe

DOI: 10.1111/pan.14257

11 / 2021

An Artificial Neural Network"Based Pediatric Mortality Risk Score: Development and Performance Evaluation Using Data From a Large North American Registry

JMIR Medical Informatics

Niema Ghanad Poor and Nicholas C West and Rama Syamala Sreepada and Srinivas Murthy and Matthias Grges

DOI: 10.2196/24079

08 / 2021

The effect of intraoperative lidocaine infusion on postoperative opioid consumption in adolescents undergoing posterior spinal instrumentation and fusion for idiopathic scoliosis

The Spine Journal

Richard Lin and Kai Zhu and Andrew K. Poznikoff and Matthias Grges and Zo E. Brown

DOI: 10.1016/j.spinee.2021.03.024

07 / 2021

News Article Portrayal of Virtual Care for Health Care Delivery in the First 7 Months of the COVID-19 Pandemic

Telemedicine Reports

Kathy L. Rush and Lindsay Burton and Mindy A. Smith and Sarah Singh and Kira Schaab and Matthias Grges and Robert Janke and Leanne M. Currie

DOI: 10.1089/tmr.2020.0033

03 / 2021

The Effect of Low-Dose Intraoperative Ketamine on Closed-Loop-Controlled General Anesthesia: A Randomized Controlled Equivalence Trial

Anesthesia & Analgesia

Gabby Napoleone and Klaske van Heusden and Erin Cooke and Nicholas West and Matthias Grges and Guy A. Dumont and J. Mark Ansermino and Richard N. Merchant

DOI: 10.1213/ane.0000000000005372

02 / 2021

A majority of uninfected adults show preexisting antibody reactivity against SARS-CoV-2

JCI Insight

Majdoubi, A. and Michalski, C. and O?Connell, S.E. and Dada, S. and Narpala, S. and Gelinas, J. and Mehta, D. and Cheung, C. and Winkler, D.F.H. and Basappa, M. and Liu, A.C. and Grges, M. and Barakauskas, V.E. and Irvine, M. and Mehalko, J. and Esposito, D. and Sekirov, I. and Jassem, A.N. and Goldfarb, D.M. and Pelech, S. and Douek, D.C. and McDermott, A.B. and Lavoie, P.M.

DOI: 10.1172/jci.insight.146316

Anesthesia in the modern world of apps and technology: Implications and impact on wellness

Paediatric Anaesthesia

Lo, C. and Yu, J. and Grges, M. and Matava, C.

DOI: 10.1111/pan.14051

The effect of ketamine on depth of hypnosis indices during total intravenous anesthesia"a comparative study using a novel electroencephalography case replay system

Journal of Clinical Monitoring and Computing

Schler, S.S. and Petersen, C.L. and West, N.C. and Ansermino, J.M. and Merchant, R.N. and Grges, M.

DOI: 10.1007/s10877-020-00565-0

Derivation and internal validation of a data-driven prediction model to guide frontline health workers in triaging children under-five in Nairobi, Kenya

Wellcome Open Research

Mawji, A. and Ansermino, M.J. and Akech, S. and Mwaniki, P. and Dunsmuir, D. and Bone, J. and Wiens, M.O. and Grges, M. and Kimutai, D. and Kissoon, N. and English, M.

DOI: 10.12688/wellcomeopenres.15387.3

Characteristics and Timing of Mortality in Children Dying With Infections in North American PICUs

Pediatric Critical Care Medicine

Johnson, K.T. and Grges, M. and Murthy, S.

DOI: 10.1097/PCC.0000000000002667

The Effect of Carbetocin Dose on Transmural Dispersion of Myocardial Repolarization in Healthy Parturients Scheduled for Elective Cesarean Delivery Under Spinal Anesthesia: A Prospective, Randomized Clinical Trial

Anesthesia and Analgesia

Clunies-Ross, N. and Roston, T.M. and Taylor, J. and Whyte, S. and Albert, A. and Grges, M. and Chau, A.

DOI: 10.1213/ANE.0000000000004712

Effect of ketamine on the NeuroSENSE WAVCNS during propofol anesthesia; a randomized feasibility trial

Journal of Clinical Monitoring and Computing

van Heusden, K. and Cooke, E. and Brodie, S. and West, N. and Grges, M. and Dumont, G.A. and Ansermino, J.M. and Merchant, R.N.

DOI: 10.1007/s10877-020-00511-0

Preferred Functions of Personal Health Records in Rural Primary Health Clinics in Canada: Health Care Team Perspectives

Applied Clinical Informatics

Grges, M. and Rush, K.L. and Burton, L. and Mattei, M. and Davis, S. and Scott, H. and Smith, M.A. and Currie, L.M.

DOI: 10.1055/s-0040-1721397

Perceptions of Personal Health Records in Rural Primary Health Clinics in Canada " Patient Perspectives

Studies in Health Technology and Informatics

Currie, L.M. and Rush, K. and Burton, L. and Mattei, M. and Grges, M.

DOI: 10.3233/SHTI210724

Antibody reactivity against SARS-CoV-2 in adults from the Vancouver metropolitan area, Canada

Abdelilah Majdoubi and Sarah E. OConnell and Christina Michalski and Sarah Dada and Sandeep Narpala and Jean Gelinas and Disha Mehta and Claire Cheung and Manjula Basappa and Matthias Grges and Vilte E Barakauskas and David M. Goldfarb and Daniel C. Douek and Adrian B. McDermott and Pascal M. Lavoie

DOI: 10.1101/2020.10.05.20206664

10 / 2020

Feasibility of Using a Single Heart Rate"Based Measure for Real-time Feedback in a Voluntary Deep Breathing App for Children: Data Collection and Algorithm Development

JMIR Perioperative Medicine

Christian L Petersen and Matthias Grges and Evgenia Todorova and Nicholas C West and Theresa Newlove and J Mark Ansermino

DOI: 10.2196/16639

09 / 2020

Grappling With Real-Time Diagnosis and Public Health Surveillance in Sepsis: Can Clinical Data Provide the Answer?

Pediatric Critical Care Medicine

Grges, M. and Kissoon, N.

DOI: 10.1097/PCC.0000000000002212

What you need to know before implementing a clinical research data warehouse: Comparative review of integrated data repositories in health care institutions

JMIR Formative Research

Gagalova, K.K. and Angelica Leon Elizalde, M. and Portales-Casamar, E. and Grges, M.

DOI: 10.2196/17687

Intravenous cannula placement in children for induction of general anesthesia: Prospective audit and identification of success factors

Paediatric Anaesthesia

Hgel, C. and Chen, J. and Poznikoff, A.K. and West, N.C. and Reimer, E. and Grges, M.

DOI: 10.1111/pan.13936

Evaluation of a digital triage platform in Uganda: A quality improvement initiative to reduce the time to antibiotic administration

PLoS ONE

Lee, V. and Dunsmuir, D. and Businge, S. and Tumusiime, R. and Karugaba, J. and Wiens, M.O. and Grges, M. and Kissoon, N. and Orach, S. and Kasyaba, R. and Ansermino, J.M.

DOI: 10.1371/journal.pone.0240092

Reducing preoperative anxiety with Child Life preparation prior to intravenous induction of anesthesia: A randomized controlled trial

Paediatric Anaesthesia

West, N. and Christopher, N. and Stratton, K. and Grges, M. and Brown, Z.

DOI: 10.1111/pan.13802

Evaluating NeuroSENSE for assessing depth of hypnosis during desflurane anesthesia: an adaptive, randomized-controlled trial,Une valuation du moniteur NeuroSENSE pour mesurer la profondeur de lhypnose pendant une anesthsie au desflurane: une tude randomise contrle adaptable

Canadian Journal of Anesthesia

Grges, M. and West, N.C. and Cooke, E.M. and Pi, S. and Brant, R.F. and Dumont, G.A. and Ansermino, J.M. and Merchant, R.N.

DOI: 10.1007/s12630-019-01522-5

Zero-heat-flux core temperature monitoring system: an observational secondary analysis to evaluate agreement with naso-/oropharyngeal probe during anesthesia

Journal of Clinical Monitoring and Computing

West, N. and Cooke, E. and Morse, D. and Merchant, R.N. and Grges, M.

DOI: 10.1007/s10877-019-00411-y

Augmented intelligence in pediatric anesthesia and pediatric critical care

Current Opinion in Anaesthesiology

Grges, M. and Ansermino, J.M.

DOI: 10.1097/ACO.0000000000000845

Human Computer Interaction Design for Mobile Devices Based on a Smart Healthcare Architecture

Advances in Computers and Software Engineering: Reviews

Liu, Pu and Fels, Sidney and West, Nicholas and G{\"{o}}rges, Matthias

DOI: 10.48550/arxiv.1902.03541

12 / 2019

Development and Implementation of the Portable Operating Room Tracker App With Vital Signs Streaming Infrastructure: Operational Feasibility Study

JMIR Perioperative Medicine

Matthias Grges and Nicholas C West and Christian L Petersen and J Mark Ansermino

DOI: 10.2196/13559

08 / 2019

A Postoperative Pain Management Mobile App (Panda) for Children at Home After Discharge: Usability and Feasibility

JMIR Perioperative Medicine

Dustin Dunsmuir and Helen Wu and Terri Sun and Nicholas C West and Gillian R Lauder and Matthias Grges and J Mark Ansermino

DOI: 10.2196/12305

07 / 2019

Optimizing Robust PID Control of Propofol Anesthesia for Children: Design and Clinical Evaluation

IEEE Transactions on Biomedical Engineering

Van Heusden, K. and Soltesz, K. and Cooke, E. and Brodie, S. and West, N. and Gorges, M. and Ansermino, J.M. and Dumont, G.A.

DOI: 10.1109/TBME.2019.2898194

An Algorithm for Early Detection of Sepsis Using Traditional Statistical Regression Modeling

Computing in Cardiology

Pawar, R. and Bone, J. and Ansermino, J.M. and Grges, M.

DOI: 10.23919/CinC49843.2019.9005699

Effects of Dexmedetomidine on Myocardial Repolarization in Children Undergoing General Anesthesia: A Randomized Controlled Trial

Anesthesia and analgesia

Grges, M. and Sherwin, E.D. and Poznikoff, A.K. and West, N.C. and Brodie, S.M. and Whyte, S.D.

DOI: 10.1213/ANE.0000000000004135

Integrating intraoperative physiology data into outcome analysis for the ACS Pediatric National Surgical Quality Improvement Program

Paediatric Anaesthesia

Grges, M. and Afshar, K. and West, N. and Pi, S. and Bedford, J. and Whyte, S.D.

DOI: 10.1111/pan.13531

Feasibility of Automated Vital Sign Instability Detection in Children Admitted to the Pediatric Intensive Care Unit

Computing in Cardiology

Seidel, G. and Murthy, S. and Peters, C. and Rostalski, P. and Grges, M.

DOI: 10.23919/CinC49843.2019.9005547

Effects of Dexmedetomidine on Blood Glucose and Serum Potassium Levels in Children Undergoing General Anesthesia: A Secondary Analysis of Safety Endpoints During a Randomized Controlled Trial

Anesthesia and Analgesia

Grges, M. and Poznikoff, A.K. and West, N.C. and Brodie, S.M. and Brant, R.F. and Whyte, S.D.

DOI: 10.1213/ANE.0000000000004154

Universal Risk Scores and Local Relevance: Feasible in the Digital Health Age?

Pediatric Critical Care Medicine

Grges, M. and Kissoon, N.

DOI: 10.1097/PCC.0000000000002004

Clinician-Driven Design of VitalPAD-An Intelligent Monitoring and Communication Device to Improve Patient Safety in the Intensive Care Unit

IEEE Journal of Translational Engineering in Health and Medicine

Flohr, L. and Beaudry, S. and Johnson, K.T. and West, N. and Burns, C.M. and Ansermino, J.M. and Dumont, G.A. and Wensley, D. and Skippen, P. and Gorges, M.

DOI: 10.1109/JTEHM.2018.2812162

External validation of the QuiCK pediatric logistic Organ Dysfunction-2 score using a large North American cohort of critically ill children with suspected infection

Pediatric Critical Care Medicine

Grges, M. and Peters, C. and Murthy, S. and Pi, S. and Kissoon, N.

DOI: 10.1097/PCC.0000000000001729

Data access and usage practices across a cohort of researchers at a large tertiary pediatric hospital: Qualitative survey study

Journal of Medical Internet Research

Ho, H.K.K. and Grges, M. and Portales-Casamar, E.

DOI: 10.2196/medinform.8724

Design and evaluation of a closed-loop anesthesia system with robust control and safety system

Anesthesia and Analgesia

West, N. and Van Heusden, K. and Grges, M. and Brodie, S. and Rollinson, A. and Petersen, C.L. and Dumont, G.A. and Mark Ansermino, J. and Merchant, R.N.

DOI: 10.1213/ANE.0000000000002663

Mortality Risk Using a Pediatric Quick Sequential (Sepsis-Related) Organ Failure Assessment Varies With Vital Sign Thresholds

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

Peters, C. and Murthy, S. and Brant, R. and Kissoon, N. and Grges, M.

DOI: 10.1097/PCC.0000000000001598

Feasibility of continuous sedation monitoring in critically ill intensive care unit patients using the NeuroSENSE WAVCNS index

Journal of Clinical Monitoring and Computing

West, N. and McBeth, P.B. and Brodie, S.M. and van Heusden, K. and Sunderland, S. and Dumont, G.A. and Griesdale, D.E.G. and Ansermino, J.M. and Grges, M.

DOI: 10.1007/s10877-018-0115-6

Effect of preoperative warming on intraoperative hypothermia: a randomized-controlled trial,Effet du rchauffement propratoire sur lhypothermie peropratoire: essai randomis contrl

Canadian Journal of Anesthesia

Lau, A. and Lowlaavar, N. and Cooke, E.M. and West, N. and German, A. and Morse, D.J. and Grges, M. and Merchant, R.N.

DOI: 10.1007/s12630-018-1161-8

In-hospital usability and feasibility evaluation of Panda, an app for the management of pain in children at home

Paediatric Anaesthesia

Sun, T. and Dunsmuir, D. and Miao, I. and Devoy, G.M. and West, N.C. and Grges, M. and Lauder, G.R. and Ansermino, J.M.

DOI: 10.1111/pan.13471

Closed-Loop Control of Total Intravenous Anesthesia During Significant Intraoperative Blood Loss

A & A Case Reports

Sonia M. Brodie and Matthias Grges and J. Mark Ansermino and Guy A. Dumont and Richard N. Merchant

DOI: 10.1213/xaa.0000000000000576

07 / 2017

Sequential allocation trial design in anesthesia: an introduction to methods, modeling, and clinical applications

Paediatric Anaesthesia

Grges, M. and Zhou, G. and Brant, R. and Ansermino, J.M.

DOI: 10.1111/pan.13088

Using physiological monitoring data for performance feedback: an initiative using thermoregulation metrics,Utilisation des donnes de monitorage physiologique pour les rtroactions sur la performance: une initiative base sur les mesures de la thermorgulation

Canadian Journal of Anesthesia

Grges, M. and West, N.C. and Whyte, S.D.

DOI: 10.1007/s12630-016-0762-3

In response

Anesthesia and Analgesia

Petersen, C.L. and Grges, M. and Massey, R. and Dumont, G.A. and Ansermino, J.M.

DOI: 10.1213/ANE.0000000000001957

An ethnographic observational study to evaluate and optimize the use of respiratory acoustic monitoring in children receiving postoperative opioid infusions

Anesthesia and Analgesia

Grges, M. and West, N.C. and Christopher, N.A. and Koch, J.L. and Brodie, S.M. and Lowlaavar, N. and Lauder, G.R. and Ansermino, J.M.

DOI: 10.1213/ANE.0000000000001127

Developing an objective method for analyzing vital signs changes in neonates during general anesthesia

Paediatric Anaesthesia

Grges, M. and West, N.C. and Karlsdttir, E. and Ansermino, J.M. and Cassidy, M. and Lauder, G.R.

DOI: 10.1111/pan.12994

A Procedural Electroencephalogram Simulator for Evaluation of Anesthesia Monitors

Anesthesia and Analgesia

Petersen, C.L. and Grges, M. and Massey, R. and Dumont, G.A. and Ansermino, J.M.

DOI: 10.1213/ANE.0000000000001506

Preoperative warming and undesired surgical and anesthesia outcomes in pediatric spinal surgery"a retrospective cohort study

Paediatric Anaesthesia

Grges, M. and West, N.C. and Cheung, W. and Zhou, G. and Miyanji, F. and Whyte, S.D.

DOI: 10.1111/pan.12939

Dexmedetomidine and hydromorphone: A novel pain management strategy for the oncology ward setting during anti-GD2 immunotherapy for high-risk neuroblastoma in children

Pediatric Blood and Cancer

Grges, M. and West, N. and Deyell, R. and Winton, P. and Cheung, W. and Lauder, G.

DOI: 10.1002/pbc.25197

Changes in QTc associated with a rapid bolus dose of dexmedetomidine in patients receiving TIVA: A retrospective study

Paediatric Anaesthesia

Grges, M. and Whyte, S.D. and Sanatani, S. and Dawes, J. and Montgomery, C.J. and Ansermino, J.M.

DOI: 10.1111/pan.12780

No BP During NIBP

09 / 2014

A scheme-based closed-loop anesthesia system

ACM International Conference Proceeding Series

Petersen, C.L. and Grges, M. and Ansermino, J.M. and Dumont, G.A.

DOI: 10.1145/2635648.2635651

Development of mHealth applications for pre-eclampsia triage

IEEE Journal of Biomedical and Health Informatics

Dunsmuir, D.T. and Payne, B.A. and Cloete, G. and Petersen, C.L. and Grges, M. and Lim, J. and Von Dadelszen, P. and Dumont, G.A. and Ansermino, J.M.

DOI: 10.1109/JBHI.2014.2301156

Using machine-to-machine / "internet of Things" communication to simplify medical device information exchange

2014 International Conference on the Internet of Things, IOT 2014

Grges, M. and Dumont, G.A. and Petersen, C.L. and Ansermino, J.M.

DOI: 10.1109/IOT.2014.7030114

Identifying a rapid bolus dose of dexmedetomidine (ED50) with acceptable hemodynamic outcomes in children

Paediatric Anaesthesia

Dawes, J. and Myers, D. and Grges, M. and Zhou, G. and Ansermino, J.M. and Montgomery, C.J.

DOI: 10.1111/pan.12468

A retrospective audit to examine the effectiveness of preoperative warming on hypothermia in spine deformity surgery patients

Paediatric Anaesthesia

Grges, M. and Ansermino, J.M. and Whyte, S.D.

DOI: 10.1111/pan.12204

Evaluation of the effect of information integration in displays for ICU nurses on situation awareness and task completion time: A prospective randomized controlled study

International Journal of Medical Informatics

Koch, S.H. and Weir, C. and Westenskow, D. and Gondan, M. and Agutter, J. and Haar, M. and Liu, D. and Grges, M. and Staggers, N.

DOI: 10.1016/j.ijmedinf.2012.10.002

An evaluation of an expert system for detecting critical events during anesthesia in a human patient simulator: A prospective randomized controlled study

Anesthesia and Analgesia

Grges, M. and Winton, P. and Koval, V. and Lim, J. and Stinson, J. and Choi, P.T. and Schwarz, S.K.W. and Dumont, G.A. and Ansermino, J.M.

DOI: 10.1213/ANE.0b013e3182975b63

Mobile patient monitoring for the pediatric intensive care unit work domain analysis and rapid prototyping results

Proceedings - 2013 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2013

Grges, M. and Burns, C.M. and Morita, P.P. and Ansermino, J.M.

DOI: 10.1109/SMC.2013.642

Experience report: Functional programming of mhealth applications

Proceedings of the ACM SIGPLAN International Conference on Functional Programming, ICFP

Petersen, C.L. and Grges, M. and Dunsmuir, D. and Ansermino, J.M. and Dumont, G.A.

DOI: 10.1145/2500365.2500615

Changes in cardiac index and blood pressure on positioning children prone for scoliosis surgery

Anaesthesia

Brown, Z.E. and Grges, M. and Cooke, E. and Malherbe, S. and Dumont, G.A. and Ansermino, J.M.

DOI: 10.1111/anae.12310

Evaluation of an integrated intensive care unit monitoring display by critical care fellow physicians

Journal of Clinical Monitoring and Computing

Grges, M. and Westenskow, D.R. and Markewitz, B.A.

DOI: 10.1007/s10877-012-9370-0

Intensive care unit nurses' information needs and recommendations for integrated displays to improve nurses' situation awareness

Journal of the American Medical Informatics Association

Koch, S.H. and Weir, C. and Haar, M. and Staggers, N. and Agutter, J. and Grges, M. and Westenskow, D.

DOI: 10.1136/amiajnl-2011-000678

University of Queensland vital signs dataset: Development of an accessible repository of anesthesia patient monitoring data for research

Anesthesia and Analgesia

Liu, D. and Grges, M. and Jenkins, S.A.

DOI: 10.1213/ANE.0b013e318241f7c0

ICU nurse's evaluations of integrated information displays on user satisfaction and perceived mental workload

Studies in Health Technology and Informatics

Koch, S.H. and Westenskow, D. and Weir, C. and Agutter, J. and Haar, M. and Gorges, M. and Liu, D. and Staggers, N.

DOI: 10.3233/978-1-61499-101-4-383

Medical device alarms

Biomedizinische Technik

Borowski, M. and Grges, M. and Fried, R. and Such, O. and Wrede, C. and Imhoff, M.

DOI: 10.1515/BMT.2011.005

A far-view intensive care unit monitoring display enables faster triage

Dimensions of Critical Care Nursing

Grges, M. and Kck, K. and Koch, S.H. and Agutter, J. and Westenskow, D.R.

DOI: 10.1097/DCC.0b013e31821b7f08

Signal processing, human factors, and modelling to support bedside care in the intensive care unit

08 / 2010

Evaluation of an ambient color coded display to communicate changes in the patient's condition to ICU nurses and improve the therapeutic environment

Proceedings of the Human Factors and Ergonomics Society

Koch, S.H. and Grges, M. and Weir, C.

DOI: 10.1518/107118110X12829370089083

Evaluation of an Ambient Color-Coded Display to Communicate Changes in the Patients Condition to ICU Nurses and Improve the Therapeutic Environment

DOI: 10.1177/154193121005401944

A tool predicting future mean arterial blood pressure values improves the titration of vasoactive drugs

Journal of Clinical Monitoring and Computing

Grges, M. and Westenskow, D.R. and Kck, K. and Orr, J.A.

DOI: 10.1007/s10877-010-9238-0

Improving alarm performance in the medical intensive care unit using delays and clinical context

Anesthesia and Analgesia

Grges, M. and Markewitz, B.A. and Westenskow, D.R.

DOI: 10.1213/ane.0b013e31819bdfbb

Evaluations of physiological monitoring displays: A systematic review

Journal of Clinical Monitoring and Computing

Grges, M. and Staggers, N.

DOI: 10.1007/s10877-007-9106-8

Using preoperative data to guide pediatric postsurgical pain management

Our goal is to use smartphones and artificial intelligence to enhance pain management for children undergoing surgery. We will combine digital health and data analytics with local patient-reported outcome measures (e.g., pain, functional recovery, and satisfaction) and patient-centred research methods to improve personalized care by developing perioperative pain trajectory prediction models and tools to communicate these to families. We hope that utilizing these tools will enhance the child’s individual care, as identifying children at high risk of pain will enable us to intervene before their surgery. This work has four phases: 1) select tools and outcomes, 2) collect baseline data and develop models, 3) develop and usability-evaluate a risk communication tool, 4) implement a digital-health-enabled pediatric prehabilitation app and pilot evaluate its effectiveness.

A bi­directional data sharing platform for researchers and citizen science

The proliferation of smartphones and home hub devices has generated vast amounts of largely untapped data and offers tremendous opportunities for the general public to contribute to scientific research and discovery. By using human-centred design processes, we will create a platform that allows researchers to share personalized research findings with the participants of research projects. Additionally, we are developing an app that will enable users to visualize data from their smartphones and other smart home or wearable devices and guide them in selecting the data they wish to donate for use by researchers in a safe and informed manner.

Co-developing a needs-derived research strategy toward forming a Digital Health Research Centre at BC Children’s and Women’s Hospitals

Digital health combines technology, such as smartphones and artificial intelligence, with data from personal devices and hospital systems, and involves people, including doctors, nurses, patients, and families, to enhance the health and well-being of the population. Digital health improves access to care and quality by providing the right information at the right time. Our team’s digital health research focuses on enhancing care for women, children, and their families in BC. We aim to develop a shared research strategy and plan for a new Digital Health Research Centre encompassing BC Children’s and Women’s Hospitals. In this project, we will identify gaps and opportunities, define priorities, and co-develop research strategies that tackle current challenges to enhance our health system with digital technology.

Assessment of Case Cancellation Equity in Surgical Scheduling

Cancelling planned surgeries can negatively affect the patient and their family. At BC Children’s Hospital, surgeries may be postponed if there aren’t enough beds available for patients after their procedures. We wonder whether patients who live farther from BC Children's experience more case postponements than those who live closer to BC Children’s Hospital. The hospital may adopt this approach to spare non-local families unnecessary travel if their surgery is likely to be postponed, which may create a health inequity. Our team aims to study whether case cancellations are related to patients’ geographical locations and to explore the impact of these cancellations on the families.

REACHOUT NexGEN: A virtual care platform for peer-led mental health support in adolescents with type 1 diabetes

The purpose of this study is to investigate the feasibility and acceptability of a virtual care platform that provides adolescents (ages 15-18) with type 1 diabetes with an accessible peer support intervention (app) to improve mental health. For three months, 40 participants will use the app and have access to 1-on-1 and group support provided by trained Peer Mentors. We will conduct surveys before and after the intervention to assess changes in mental health and well-being. After the intervention, we will conduct usability and satisfaction surveys to assess the acceptability of the intervention.

Grants

2025-09, Formation of the Artificial Intelligence and Data Science Unit at the BC Children’s Hospital Research Institute, Digital Health and Data Analytics Super Hub, BC Children’s Hospital Research Institut

2025-06, Pilot Deployment of Language Models at BC Children’s Hospital Research Institute, Digital Health and Data Analytics Super Hub, BC Children’s Hospital Research Institute

2025-03, Evidence to Innovation Seed Grant, BC Children’s Hospital Research Institute

2024-10, Convening & Collaborating Program, Michael Smith Health Research BC

2021-07, C&W Digital Health Research Accelerator Grant, BC Children’s Hospital Research Institute

2021-04, Discovery Grant, Natural Sciences and Engineering Research Council of Canada (NSERC)

2020-07, Scholar Program, Michael Smith Health Research BC

Honours & Awards

2025-07, Recommendation for Outstanding Academic Performance (OAP) for the 2024 calendar year, University of British Columbia

2025-05, Department of Anesthesiology, Pharmacology and Therapeutics - Paper of the Year, University of British Columbia

2024-09, Peer-Mentorship Excellence by an Investigator, BC Children’s Hospital Research Institute

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