I am clinically involved at BCCH in the care of children with congenital heart disease as both a cardiac anesthesiologist and a critical care physician. I have a strong interest and significant training and experience in cardiovascular anesthesia and critical care. My primary focus is the study of anesthesia and critical care in children with congenital heart disease.
Transfusion-related acute lung injury in the Canadian paediatric population Paediatrics and Child Health (Canada) Gauvin, F. and Robillard, P. and Hume, H. and Grenier, D. and Whyte, R.K. and Webert, K.E. and Fergusson, D. and Lau, W. and Froese, N. and Delage, G. DOI: 10.1093/pch/17.5.235 2012
Does troponin-I measurement predict low cardiac output syndrome following cardiac surgery in children? Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine Froese, N.R. and Sett, S.S. and Mock, T. and Krahn, G.E. 2009
Cardiac Preload Indicators in Children The assessment of intravascular volume status in children is a difficult task guided by minimal scientific evidence. Administration of intravenous fluid to hemodynamically unstable and anesthetised children is a common therapeutic intervention. Much evidence exists of the danger of indiscriminate intravenous fluid loading. Dynamic preload indicators have been demonstrated in adults to represent a good indicator of volume status, but little evidence exists in children.
We aim to compare the ability of static preload indicators (central venous pressure and pulmonary capillary wedge pressure) with less invasive dynamic indicators (pulse pressure variation, plethysmograph variation) to predict the cardiac output response to a fluid bolus. The ultimate aim of this study is to help improve the safety of fluid administration for sick children.
Post Cardiac Surgery Blood Loss When a child undergoes heart surgery, a heart lung machine is used to keep blood flowing while the child’s own heart is stopped. After surgery, a significant amount of the child’s own blood is left in this machine. In the case of small children, the relative amount of blood potentially lost to the child in this way is very large.
In older children, and those who have undergone less complicated surgery, this blood can all returned to the child. Giving the child back his or her own blood makes is less likely that the child will need a transfusion of donated blood.
However, in younger children, or in children who have undergone more complicated surgery, most or all of this blood is thrown away. This is because of worry that returning this blood may cause bleeding, and excessive bleeding is one of the most feared complications of heart surgery.
This project will explore a method whereby the red blood cells left in the heart lung machine can be returned to children without increasing the risk of bleeding. It will also carefully examine the exact causes of higher bleeding risk in children getting their own blood back so that in the future, all children can have their own blood returned at the end of surgery.
There are currently no evidence-based guidelines for medical marijuana use in pediatric patients. Dr. Rod Rassekh is focused on research that will provide better understanding on the risks and potential benefits of therapeutic cannabis.
Vaccine hesitancy is complex with many factors influencing caregivers’ decisions on vaccinations. New research shows unvaccinated parents may be willing to vaccinate their children and should be included in public health messaging.
Hydroxyzine is a first-generation antihistamine commonly prescribed in syrup form to infants and young children with itch-inducing skin conditions, such as atopic dermatitis and eczema. New research shows that the more hydroxyzine a child is prescribed, the higher their risk for developing a tic, anxiety, or conduct disorder.
BC Children’s Hospital investigator and UBC associate professor Dr. Mariana Brussoni has been awarded an additional $1.3 million for her ongoing project to maximize outdoor play time for early learning and child care centres to support pandemic management and preparedness activities.
We believe there’s nothing we can’t do with your support. It can take years to turn scientific breakthrough into new interventions and treatments. Funding helps speed the pace of change. When given the resources, we can bring transformative therapies – and hope – out of the laboratory and into the clinic to save and improve children’s lives.