- Overview
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My research interests are focused on improving care for hospitalized children. In particular, I aim to provide risk stratification tools that allow physicians to safely allocate precious clinical resources to high-risk patients.
Additionally, I have been interested in expediting evidence synthesis and shortening the process of implementing research findings in clinical practice. Along with a multi-disciplinary team from BC Children’s Hospital and CHEO (Ottawa, ON), I have launched a platform to crowdsource the systematic review process and provide an up-to-date living synthesis of evidence. This has allowed me to identify current knowledge gaps that will help to guide future research questions.
- Publications
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Identifying serious underlying diagnoses among patients with brief resolved unexplained events (BRUEs): a Canadian cohort study
BMJ Paediatrics Open
Nassr Nama and Zerlyn Lee and Kara Picco and Falla Jin and Jeffrey N Bone and Julie Quet and Jessica Foulds and Josée Anne Gagnon and Chris Novak and Brigitte Parisien and Matthew Donlan and Ran D Goldman and Anupam Sehgal and Ronik Kanani and Joanna Holland and Polina Kyrychenko and Nardin Kirolos and Ioulia Opotchanova and Émilie Harnois and Alyse Schacter and Elisa Frizon-Peresa and Praveen Rajasegaran and Parnian Hosseini and Melody Wyslobicky and Susan Akbaroghli and Prathiksha Nalan and Sanjay Mahant and Joel Tieder and Peter Gill
DOI: 10.1136/bmjpo-2024-002525
09/2024Challenges in Validation of Novel Diagnostic Tools for Pediatric Pneumonia: When Will We Find "The One"?
Hospital Pediatrics
DOI: 10.1542/HPEDS.2024-008040
2024Trends in the use and discussion of race in pediatrics articles over 75 years
Pediatrics
DOI: 10.1542/peds.2023-064819
2024Epidemiology of brief resolved unexplained events and impact of clinical practice guidelines in general and pediatric emergency departments
Academic Emergency Medicine
DOI: 10.1111/acem.14881
2024Brief Resolved Unexplained Event: Evidence-Based and Family-Centered Management
Pediatrics in Review
DOI: 10.1542/PIR.2024-006351
2024Conservative and Surgical Modalities in the Management of Pediatric Parapneumonic Effusion and Empyema: A Living Systematic Review and Network Meta-Analysis
Chest
DOI: 10.1016/j.chest.2023.06.010
2023Short duration of parenteral antibiotics in infants with urinary tract infections
Paediatrics and Child Health (Canada)
DOI: 10.1093/pch/pxad030
2023Canadian infants presenting with Brief Resolved Unexplained Events (BRUEs) and validation of clinical prediction rules for risk stratification: A protocol for a multicentre, retrospective cohort study
BMJ Open
DOI: 10.1136/bmjopen-2022-063183
2022Risk Prediction After a Brief Resolved Unexplained Event
Hospital Pediatrics
Nama, N. and Hall, M. and Neuman, M. and Sullivan, E. and Bochner, R. and De Laroche, A. and Hadvani, T. and Jain, S. and Katsogridakis, Y. and Kim, E. and Mittal, M. and Payson, A. and Prusakowski, M. and Shastri, N. and Stephans, A. and Westphal, K. and Wilkins, V. and Tieder, J.
DOI: 10.1542/hpeds.2022-006637
2022Duration of Antibiotic Therapy for the Management of Urinary Tract Infections in Newborns and Young Infants Aged Under 3 Months: A Living Systematic Review and Meta-analysis Using Crowdsourcing
Pediatrics
2022Brief Resolved Unexplained Event (BRUE): Is Reassurance Enough for Caregivers?
Hospital Pediatrics
Nama, N. and DeLaroche, A.M. and Gremse, D.A.
DOI: 10.1542/hpeds.2022-006939
2022Successful incorporation of single reviewer assessments during systematic review screening: development and validation of sensitivity and work-saved of an algorithm that considers exclusion criteria and count
Systematic Reviews
Nama, N. and Hennawy, M. and Barrowman, N. and O?Hearn, K. and Sampson, M. and McNally, J.D.
DOI: 10.1186/s13643-021-01632-6
2021Evaluating the relationship between citation set size, team size and screening methods used in systematic reviews: a cross-sectional study
BMC Medical Research Methodology
O?Hearn, K. and MacDonald, C. and Tsampalieros, A. and Kadota, L. and Sandarage, R. and Jayawarden, S.K. and Datko, M. and Reynolds, J.M. and Bui, T. and Sultan, S. and Sampson, M. and Pratt, M. and Barrowman, N. and Nama, N. and Page, M. and McNally, J.D.
DOI: 10.1186/s12874-021-01335-5
2021Conservative and surgical modalities in the management of paediatric parapneumonic effusion and empyema: A protocol for a living systematic review and network meta-Analysis
BMJ Open
DOI: 10.1136/bmjopen-2020-045010
2021Creating enriched training sets of eligible studies for large systematic reviews: the utility of PubMed’s Best Match algorithm
International Journal of Technology Assessment in Health Care
Sampson, M. and Nama, N. and O?Hearn, K. and Murto, K. and Nasr, A. and Katz, S.L. and Macartney, G. and Momoli, F. and McNally, J.D.
DOI: 10.1017/S0266462320002159
2021Treatment of UTIs in infants <2 months: A living systematic review
Hospital Pediatrics
DOI: 10.1542/hpeds.2021-005877
2021Live Scoping Review of N95 and Surgical Facemask Decontamination and Reuse: A Scoping Review Protocol
Katie O'Hearn and Anirudh Agarwal and Karen Choong and Shira Gertsman and Nassr Nama and Margaret Sampson and Lindsey Sikora and David J Zorko and James Dayre McNally
DOI: 10.31219/osf.io/rpc27
05/2020Vincristine-induced peripheral neurotoxicity: A prospective cohort
Pediatric Hematology and Oncology
Nama, N. and Barker, M.K. and Kwan, C. and Sabarre, C. and Solimano, V. and Rankin, A. and Raabe, J. and Ross, C.J. and Carleton, B. and Zwicker, J.G. and Rassekh, S.R.
DOI: 10.1080/08880018.2019.1677832
2020Quality control for crowdsourcing citation screening: the importance of assessment number and qualification set size
Journal of Clinical Epidemiology
Nama, N. and Barrowman, N. and O'Hearn, K. and Sampson, M. and Zemek, R. and McNally, J.D.
DOI: 10.1016/j.jclinepi.2020.02.009
2020Identification and Evaluation of Controlled Trials in Pediatric Cardiology: Crowdsourced Scoping Review and Creation of Accessible Searchable Database
Canadian Journal of Cardiology
Ashkanase, J. and Nama, N. and Sandarage, R.V. and Penslar, J. and Gupta, R. and Ly, S. and Wan, M. and Tsang, P. and Nantsios, A. and Jacques, E. and Yang, H.Y. and Tsang, C.I. and Mazhar, H. and Xu, G. and Rodriguez, M. and Gerber, S. and Laird, L.M. and Sampson, M. and Wong, D.T. and McNally, J.D.
DOI: 10.1016/j.cjca.2020.01.028
2020Crowdsourcing the citation screening process for systematic reviews: Validation study
Journal of Medical Internet Research
Nama, N. and Sampson, M. and Barrowman, N. and Sandarage, R. and Menon, K. and Macartney, G. and Murto, K. and Vaccani, J.-P. and Katz, S. and Zemek, R. and Nasr, A. and McNally, J.D.
DOI: 10.2196/12953
2019LGBT Patients and Families Health Issues: Medical Students' Attitudes and the Inclusivity of Medical School
Pediatrics
DOI: 10.1542/PEDS.142.1_MEETINGABSTRACT.791
2018Ligand-specific conformational transitions and intracellular transport are required for atypical chemokine receptor 3-mediated chemokine scavenging
Journal of Biological Chemistry
DOI: 10.1074/JBC.M117.814947
2018Vitamin D deficiency in critically ill children: A systematic review and meta-analysis
Critical Care
McNally, J.D. and Nama, N. and O'Hearn, K. and Sampson, M. and Amrein, K. and Iliriani, K. and McIntyre, L. and Fergusson, D. and Menon, K.
DOI: 10.1186/s13054-017-1875-y
2017A pilot validation study of crowdsourcing systematic reviews: Update of a searchable database of pediatric clinical trials of highdose Vitamin D
Translational Pediatrics
Nama, N. and Iliriani, K. and Xia, M.Y. and Chen, B.P. and Zhou, L.L. and Pojsupap, S. and Kappel, C. and O'Hearn, K. and Sampson, M. and Menon, K. and McNally, J.D.
DOI: 10.21037/tp.2016.12.01
2017Medical students' perception of lesbian, gay, bisexual, and transgender (LGBT) discrimination in their learning environment and their self-reported comfort level for caring for LGBT patients: A survey study
Medical Education Online
Nama, N. and MacPherson, P. and Sampson, M. and McMillan, H.J.
DOI: 10.1080/10872981.2017.1368850
2017A systematic review of pediatric clinical trials of high dose vitamin D
PeerJ
Nama, N. and Menon, K. and Iliriani, K. and Pojsupap, S. and Sampson, M. and O'Hearn, K. and Zhou, L. and McIntyre, L. and Fergusson, D. and McNally, J.D.
DOI: 10.7717/peerj.1701
2016THE PEPTIDOMIMETIC TC14012, AN INVERSE AGONIST ON CXCR4-beta-ARRESTIN2 PATHWAY
Journal of Receptors and Signal Transduction
2013 - Research
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Brief Resolved Unexplained Events (BRUEs)
Along with an international collaboration, I am completing a project to identify infants with a serious diagnosis among those presenting with a BRUE. The derived algorithm will be implemented in a multicenter quality improvement project across North America.Urinary Tract Infections (UTIs)
Our team has recently completed a systematic review on the effective duration of treatment for neonates with urinary tract infections. I am currently collaborating locally with members of the Division of General Pediatrics and Infectious Disease to shorten the length of hospital stay and treatment duration for these patients as a quality improvement.Crowdsourcing Systematic Reviews
Using an innovative crowdsourcing approach, our team has been able to accelerate the process of evidence synthesis, leading to the completion of systematic reviews within a short period of time. To date, we have completed several systematic reviews targeting the treatment of UTIs, the treatment of pneumonia, the role of high-dose vitamin D, and a database of all available pediatric cardiac RCTs. As an example, we completed the systematic review on UTI treatment with a crowd from 13 different countries, and spanning 5 different continents. The crowd was able to screen more than 10,000 publications within 2-3 weeks.Grants2021 – American Academy of Pediatrics Resident Research Grant – Derivation and Validation of a Clinical Prediction Rule to Determine Risk in Infants experiencing a Brief Resolved Unexplained Events (BRUEs). Nama N, Tieder JS
2021 – Resident Doctors of BC Innovation Fund – Treatment of urinary tract infections in infants under 3 months of age: A living meta-analysis. Nama N, Donken R, Sadarangani M, and Carwana M
2020 – BC Children’s Hospital Resident Research Grant – Treatment of urinary tract infections in infants under 3 months of age: A living meta-analysis. Nama N, Carwana M
2019 – BC Children’s Hospital Resident Research Grant – Peripheral Neuropathy with Vincristine: A Prospective Cohort. Nama N, Rassekh SR
2016 – CHEO Research Growth Award – Crowdsourcing Systematic Reviews: A Proof of Concept Validation Study. McNally JD, Nama N, Sampson M, Momoli F, Barrowman N, Menon K, Nasr A, Macartney G, Murto K, Vaccani J-P, Zemek R, Henderson M
Honours & Awards2021 – Friedman Award for Scholars in Health – Infants most at risk for a serious diagnosis explaining a brief resolved unexplained event. Nama N, Tieder JS
2021 – University of British Columbia – UGME Resident/Fellow Teaching Award
Research Group MembersZerlyn Lee
Cutting-edge genomic technology to help improve medication safety for children in new BC Children’s led study
Dr. Bruce Carleton will be leading a new $17 million project to make medications safer for children across Canada. By uncovering the genetic variations in patients that can lead to adverse drug reactions, this research could help explain differing medication responses and improve disease outcomes.
