• Heran, Manraj Kanwal Singh


    Investigator, BC Children's Hospital
    Staff Pediatric Interventional Radiologist, BC Children's Hospital
    Head and Associate Professor, Division of Neuroradiology, Vancouver General Hospital
    Associate Professor, Department of Radiology, University of British Columbia

    Degrees / Designations
    Primary Area of Research
    Evidence to Innovation
    Secondary Area(s) of Research
    Lab Phone
    Ms. Patricia Jimenez
    Assistant Phone
    Mailing Address

    BC Children's Hospital
    Department of Radiology
    4480 Oak Street
    Vancouver, BC, V6H 3V4

    Affiliate Websites
    Research Areas

    The role of interventional radiology in the care of pediatric patients.


    I am involved in using imaging guidance tools , such as CT, MRI, fluoroscopy, and ultrasound, in diagnosing and treating children with a wide variety of illnesses. This, together with advances in other technologies, allows for a greater number of conditions which can be treated through minimally invasive approaches. These image-guided therapies can aid or avoid other forms of treatment, including surgery or conventional medication administration.

    My joint position at Vancouver General Hospital allows for a unique opportunity to access resources for children with brain and spine disorders, especially conditions involving the vasculature. In addition, children with cancer and other complex vascular disorders can be offered treatments which would otherwise be extremely difficult to access.

    Current Projects

    My joint position at BC Children's Hospital and Vancouver General Hospital provides me with a unique opportunity to interact with a number of colleagues in numerous areas of clinical and academic medicine. At BCCH, my primary focus is imaged-guided therapy. Although this sounds somewhat vague, it actually is appropriate in that new and novel opportunities to enhance the care of children are often driven by innovation and collaboration. Through my involvement in all facets of interventional radiology, many seemingly obvious treatment strategies used in the adult population provide the reference for adaptation into the pediatric setting. As a member of the Society of Pediatric Interventional Radiology and the SIR Pediatric Interventional Radiology Standards Subcommittee, we routinely audit pediatric IR practices, and create documents for "best practice" guidelines.

    Within the UBC and BCCH setting, I am currently involved in a retrospective review of all the percutaneous pediatric liver biopsies performed in the past 10 years, with the goal being to determine low- and high-risk populations, as well as the need for hospital admission and/or blood transfusion. I am also involved with a Department of Anesthesia project at BCCH comparing pulse oximetry techniques to thermodilution methods in determination of cardiac output in various pediatric disease states.

    As a member of the Vascular Anomalies Clinic at BCCH, I am very active in the workup and management of children with vascular malformations/anomalies. Together with Dr. Douglas Courtemanche (Head, Vascular Anomalies Clinic), we have been working towards formalizing our patient assessments and followup, thereby allowing improved prospective analysis of treatment outcomes, as well as natural history. Several publications and presentations have come from our work.

    My strong relationship with Pediatric General Surgery and the pediatric neuroscience community have resulted in numerous collaborations that focus on innovation and adaptation of techniques into the pediatric setting. Currently, Dr. Erik Skarsgard and I are completing a submission on the use of embolic microcoils as a method of aiding the localization of subpleural pulmonary nodules for resection by a VATS procedure.

    Selected Publications

    "Calcified cerebral emboli"
    EC Kavanagh, DM Fenton, MKS Heran, JS Lapointe, RA Nugent, DA Graeb.
    Division of Neuroradiology, Department of Radiology, Vancouver General Hospital, Vancouver, BC
    AJNR 2006, 27:1996-1999

    "Treatment of cystic lymphatic vascular malformations with OK-432 Sclerotherapy"
    DA Peters, DJ Courtemanche, MKS Heran, JP Ludemann, JS Prendiville
    Plastic and Reconstructive Surgery 2006, 118(6): 1441-1446

    "Brain blood flow in the neurologic determination of death: Canadian expert report"
    SD Shemie, D Lee, M Sharpe, D Tampieri, B Young, MKS Heran (on behalf of Canadian Critial Care Society)
    Canadian Journal of Neurologic Sciences 2008: 35(2):140-145

    "A Review of Ancillary Tests in Evaluating Brain Death"
    MKS Heran1, NS Heran2, SD Shemie3
    Canadian Journal of Neurological Sciences 2008: 35:409-419

    "Minimally invasive techniques in management of hepatic neuroendocrine metastatic disease"
    DM Liu, A Kennedy, D Turner, SC Rose, ST Kee, S Whiting, R Murthy, C Nutting, MKS Heran, R Lewandowski, J Knight, S Gulec, R Salem
    American Journal of Clinical Oncology 2009;32(2):200-15

    "Quality improvement guidelines for pediatric arterial access and arteriography"
    Society of Interventional Radiology Standards of Practice Committee
    MKS Heran, F Marshalleck, M Temple, et al
    JVIR 2010;21(1):32-43

    "Neuroangiography in Children"
    MKS Heran, MJ Alexander
    Pediatric Neurovascular Disease: Surgical, Endovascular, and Medical Management
    Thieme, New York (2006)
    Editors: Dr. Michael J. Alexander, Robert F. Spetzler
    Duke University Medical Center

    "Current Concepts and Techniques in Percutaneous Vertebroplasty"
    MKS Heran, GM Legiehn, PL Munk
    Orthopedic Clinics of North America
    Guest Editor: Dr. Peter L. Munk
    Orthopedic Clinics of North America 2006;37(3):409-434,vii

    "Classification, Diagnosis and Interventional Radiologic Management of Vascular Malformations"
    GM Legiehn, MKS Heran
    Orthopedic Clinics of North America
    Guest Editor: Dr. Peter L. Munk
    Orthopedic Clinics of North America 2006;37(3):435-474,vii-viii

    "Spinal Injection Procedures: Concepts, Controversies, and Complications"
    MKS Heran, AD Smith, GM Legiehn
    Radiologic Clinics of North America
    Guest Editor: Dr. Peter L. Munk
    Radiologic Clinics of North America, May 2008: 46(3):487-514

    Honours & Awards
    Best Teaching by a Non-Neurologist, University of British Columbia Neurology Residency Program, 2009-2010.

    Honorable Mention (Posters) "Embolic and sclerosing agents: what the pediatric radiologist should know"
    J Dubois1, MKS Heran2, P John3, J Racadio4, AM Cahill5, M Sidhu6
    Accepted for poster presentation (SPR, Carlsbad, April, 2009)

    Certificate of Appreciation, Career Counselling Program, Faculty of Medicine, University of British Columbia, 2009

    Best Lecturer, University of British Columbia Radiology Residency Program: 2007-2008

    Certificate of Distinction, University of British Columbia Faculty of Medicine (2007)

    Outstanding Shadow Preceptor Award, Vancouver Fraser Medical Program, Faculty of Medicine, University of British Columbia, 2007

    Family-Centered Care: Honourable Mention for Patient Care, BC Children’s Hospital, 2007

    Best Noon Teaching Rounds, University of British Columbia Radiology Residency Program: 2005-2006

    Chief Resident, Diagnostic Radiology Residency, University of British Columbia (2001-2002)

    Chief Resident, Diagnostic Radiology Residency, University of British Columbia (2000-2001)
    Research Group Members