Ram Mishaal

MD

Investigator, BC Children's Hospital
Senior Medical Director, Child Development and Rehabilitation, Sunny Hill Health Centre, BC Children's Hospital

As the Senior Medical Director of Child Development and Rehabilitation at BC Children’s Hospital (BCCH)/ Sunny Hill Health Centre , and the Medical Director of the Neuromotor Program , Dr. Mishaal’s main clinical research interests involve neuromotor rehabilitation and cerebral palsy for children and youth. He leads the CP Early Diagnosis Initiative, including the provincial Early Motor Screening Program and the CP Early Diagnosis Clinic, he is the BC site investigator for the Canadian Cerebral Palsy Registry, and is an investigator on multiple CP, rehabilitation and child development projects. He has also been the founder and lead of the Specialized Pediatric Rehabilitation OUTpatient (SPROUT) program at BCCH.

Academic Affiliations

  • Clinical Assistant Professor, Division of Developmental Pediatrics, Department of Pediatrics, Faculty of Medicine, University of British Columbia
  • Research Theme: Brain, Behaviour & Development
  • Research Group(s): Mental Health and Behaviour; Neurodevelopmental and Neurological Disorders; Visualizing the Brain

Contact Information

Location

4500 Oak Street, Vancouver, British Columbia, Canada, V6H 3N1

Trying to be an Early BIRD: An exploration of factors impacting British Columbia's intervention referral and diagnosis of cerebral palsy

Paediatrics and Child Health Canada

Mcintosh, T. and Wong, V. and Sandhu, A. and Cohen-Eilig, M. and Mishaal, R.

DOI: 10.1093/pch/pxae076

Investigating Pediatricians Practice, Knowledge, and Barriers in Diagnosing Cerebral Palsy

Children

Wong, V. and Miller, S.D. and Scoten, O. and Cohen-Eilig, M. and Glegg, S. and Ip, A. and Jetha, C. and Mulpuri, K. and O?Donnell, M. and Mishaal, R.

DOI: 10.3390/children12091274

Clinical Phenotype, Predictors and Early Biomarkers of Dyskinetic Cerebral Palsy Prognosis

Pediatric Neurology

D{'}Amours, V. and Husein, N. and Dunbar, M. and Fehlings, D. and Mishaal, R. and Shevell, M. and Andersen, J. and Buckley, D. and Kirton, A. and Koclas, L. and Oskoui, M. and Pigeon, N. and Wood, E.

DOI: 10.1016/j.pediatrneurol.2025.08.008

Antenatal Corticosteroids and Child Neurodevelopment A Systematic Review and Meta-analysis

Obstetrics and Gynecology

Liauw, J. and Campbell, K.S.J. and Foggin, H. and Grunau, R.E. and Petrie, J. and Qasim, A. and Brignardello-Petersen, R. and Mishaal, R.A. and Hutcheon, J.A.

DOI: 10.1097/AOG.0000000000005950

Baclofen and Botulinum Toxin A Use in Tone Management for Children With Cerebral Palsy: A Review of Current Literature and Research Gaps in Pre- and Perioperative Care

Pediatric Neurology

Li, M. and Rozen, N. and Wortley, K. and Mishaal, R.

DOI: 10.1016/j.pediatrneurol.2025.07.018

A new care pathway for the diagnosis of cerebral palsy among community pediatricians

Paediatrics and Child Health Canada

Scoten, O. and Wong, V. and Cohen-Eilig, M. and Mishaal, R.A.

DOI: 10.1093/pch/pxae108

Clinical Application of Phage Immunoprecipitation Sequencing to Diagnose Enterovirus D68 as the Underlying Etiology in a Case of Guillain-Barr Syndrome

Journal of Infectious Diseases

Li, F.F. and Faber, A. and Caleta, J.M. and Goldfarb, D.M. and Sekirov, I. and Prystajecky, N.A. and Srigley, J.A. and Mishaal, R. and Jassem, A.N.

DOI: 10.1093/infdis/jiae411

Stability of the Gross Motor Function Classification System over time in children with cerebral palsy

Developmental Medicine & Child Neurology

Menal Huroy and Tarannum Behlim and John Andersen and David Buckley and Darcy Fehlings and Adam Kirton and Nicole Pigeon and Ram A. Mishaal and Ellen Wood and Michael Shevell and Maryam Oskoui

DOI: 10.1111/dmcn.15375

08 / 2022

Appraising the need for audiological assessment before autism spectrum disorder referral

Paediatrics and Child Health (Canada)

Mishaal, R.A. and Weikum, W.M. and Brooks, B. and Derry, K. and Lanphear, N.E.

DOI: 10.1093/pch/pxab097

Oxytocin for the treatment of autism spectrum disorder in children,Ocytocine pour le traitement du trouble du spectre de l'autisme chez les enfants

Canadian Family Physician

Griffiths, J.L. and Mishaal, R.A. and Nabetani, M. and Goldman, R.D.

DOI: 10.46747/cfp.6802106

Oxytocin for the treatment of autism spectrum disorder in children

Canadian Family Physician

Griffiths, J.L. and Mishaal, R.A. and Nabetani, M. and Goldman, R.D.

DOI: 10.46747/cfp.6802103

Baclofen Toxicity in Children With Acute Kidney Injury: Case Reports and Review of the Literature

Child Neurology Open

Ram A. Mishaal and Nancy E. Lanphear and Erez Armarnik and Esias R. van Rensburg and Douglas G. Matsell

DOI: 10.1177/2329048X20937113

01 / 2020

Age of autism spectrum disorder diagnosis is associated with child's variables and parental experience

Research in Autism Spectrum Disorders

Mishaal, R.A. and Ben-Itzchak, E. and Zachor, D.A.

DOI: 10.1016/j.rasd.2014.04.001

Is there clinical benefit to routine enzyme testing of patients on statins?

Expert Opinion on Drug Safety

Elhayany, A. and Mishaal, R.A. and Vinker, S.

DOI: 10.1517/14740338.2012.630659

Renal failure and low molecular weight heparins. A dangerous liaison? The case of retroperitoneal hematoma

Israel Medical Association Journal

Szyper Kravitz, M. and Mishaal, R.A. and Shoenfeld, Y.

Canadian Cerebral Palsy Registry

The national Canadian Cerebral Palsy (CP) Registry is a nation-wide collection of medical and social information about children with cerebral palsy. BC Children’s Hospital is the partner representing the province of BC where Dr. Mishaal has been the primary site investigator since July 2020. His team is currently undertaking an analysis using data from the Registry with the hopes of creating a general profile of BC children and youth diagnosed with CP, and exploring how different medical and environmental factors impact the age of diagnosis and the age of referral for interventions.

Understanding the Etiology of Cerebral Palsy and the Influence of Genetic Etiology on Hip Displacement

A project in collaboration with Child Health BC to explore the etiologies of cerebral palsy in the hip surveillance registry population. Data analysis stage. Co-investigator since Aug 2021.

Estimating Prevalence and Incidence of Cerebral Palsy (CP) in Children and Youth in BC

In collaboration with Child Health BC, this study uses multiple, linked, health administrative databases and predictive modelling to estimate the prevalence and incidence of CP in children and youth in BC. These estimates will inform recruitment into the Hip Surveillance Clinical Program, and select indicators will be collected for ongoing population-level surveillance.

BCI- Brain Computer Integration Study

As part of the Canadian BCI group (Led by Dr. Adam Kirton, University of Calgary). The technology has been used in 3 sites in Canada and currently we are working on doing a pilot in 3 other sites.

Evaluating the Early Motor Screening Program (EMSP)

Data analysis of outcomes, correlation between age of diagnosis, risk factors and socio-demographic factors, and analysis of the potential environmental and economic benefits of doing remote assessments (virtual)

Baclofen - Pilot (Non-Randomized) Trial

Using an intervention and control group, to provide evidence regarding the safety and effectiveness of increasing Baclofen dose prior to Orthopedic surgery.

Experiences of Parents and Caregivers with the Remote General Movement Assessment for Early Cerebral Palsy Diagnosis.

Virtual CIMT Study

Development of virtual reality functional Constraint Induced Movement Therapy (CIMT) module and neuro/biofeedback based treatment for hemiparesis in cerebral palsy. Partnered with Tel-Aviv Medical Centre, Tel-Aviv University, Israel.

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