Below are research highlights from the Sanatani Lab. You can find the full list of Shubhayan Sanatani’s publications here.
Life-Threatening Cardiac Arrhythmia and Sudden Death During Electronic Gaming: AN International Case Series and Systematic Review
Heart Rhythm
Lawley CM, Tester M, Sanatani S, Prendiville T, Beach CM, Vinocur JM, Horie M, Uhm JS, Khongphatthanayothin A, Ayers MD, Starling L, Yoshida Y, Shah MJ, Skinner JR, Turner C.
DOI: 10.1016/j.hrthm.2022.08.003
2022
Importance of Genetic Testing in Unexplained Cardiac Arrest
European Heart Journal
Grondin S, Davies B, Cadrin-Tourigny J, Steinberg C, Cheung CC, Jorda P, Healey JS, Green MS, Sanatani S, Alqarawi W, Angaran P, Arbour L, Antiperovitch P, Khan H, Leather R, Guerra PG, Rivard L, Simpson CS, Gardner M, MacIntyre C, Seifer C, Fournier A, Joza J, Gollob MH, Lettre G, Talajic M, Laksman ZW, Roberts JD, Krahn AD, Tadros R.
DOI: 10.1093/eurheartj/ehac145
2022
One Family's Clinical Odyssey from Evolving Phenotypic and Genotypic Knowledge of Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome
Heart Rhythm
Johnsrude CL, Roberts JD, Roston TM, Russell B, Franciosi S, Sanatani S.
DOI: 10.1016/j.hrcr.2022.07.006
2022
Faintly Tired: A Systematic Review of Fatigue in Patients with Orthostatic Syncope
Clinical Autonomic Research
Wu REY, Khan FM, Hockin BCD, Lobban TCA, Sanatani S, Claydon VE.
DOI: 10.1007/s10286-022-00868-z
2022
An International Multi-Center Cohort Study on β-blockers for the Treatment of Symptomatic Children with Catecholaminergic Polymorphic Ventricular Tachycardia
Circulation
Peltenburg PJ, Kallas D, Bos JM, Lieve KVV, Franciosi S, Roston TM, Enjoy I, Sorensen KB, Ohno S, Noguer FR, Aiba T, Maltret A, LaPage MJ, Atallah J, Giudicessi JR, Clur SB, Blom NA, Tanck M, Extramiana F, Kato K, Barc J, Borggrefe M, Behr ER, Sarquella-Brugada G, Tfelt-Hansen J, Zorio E, Swan H, Kammeraad JAE, Krahn AD, David A, Sacher F, Scwartz PJ, Roberts JD, Skinner JR, van den Berg MP, Kannankeril PJ, Drago F, Robyns T, Haugaa K, Tavacova T, Semsarian C, Till J, Probst V, Brugada R, Shimizu W, Horie M, Leenhardt A, Ackerman MJ, Sanatani S, van der Werf C, Wilde AAM.. DOI:10.1161/CIRCULATIONAHA.121.056018
2021
Evaluation of Age at Symptom-Onset, Proband Status and Sex as Predictors of Disease Severity in Pediatric Catecholaminergic Polymorphic Ventricular Tachycardia
Heart Rhythm
Kallas D, Roston TM, Franciosi S, Brett L, Lieve KVV, Kwok SY, Kannankeril PJ, Krahn AD, LaPage MJ, Etheridge S, Hill A, Johnsrude C, Perry J, Knight L, Fischbach P, Balaji S, Tisma-Dupanovic S, Law I, Atallah, J, Backhoff D, Kamp A, Kubus P, Kean A, Aziz PF, Kovach J, Lau Y, Kron J, Clur S, Sarquella-brugada G, Wilde AAM, Sanatani S.
Doi:10.1016/j.hrthm.2021.07.061
2021
Burst Exercise Testing Can Unmask Arrhythmias in Patients With Incompletely Penetrant Catecholaminergic Polymorphic Ventricular Tachycardia
JACC
Roston TM, Kallas D, Davies B, Franciosi S, De Souza AM, Laksman ZW, Sanatani S, Krahn AD. JACC. Clinical electrophysiology.
Doi: 10.1016/j.jacep.2021.02.013.
2021
Pediatric Catecholaminergic Polymorphic Ventricular Tachycardia: A Translational Perspective for the Clinician-Scientist
Pediatric Int J Mol Sci.
Kallas D, Lamba A, Roston TM, Arslanova A, Franciosi S, Tibbits GF, Sanatani S.
DOI: 10.3390/ijms22179293.
2021
Human RyR2 (Ryanodine Receptor 2) Loss-of-Function Mutations
Circulation: Arrhythmia and Electrophysiology
Yanhui Li and Jinhong Wei and Wenting Guo and Bo Sun and John Paul Estillore and Ruiwu Wang and Ayhan Yoruk and Thomas M. Roston and Shubhayan Sanatani and Arthur A.M. Wilde and Michael H. Gollob and Jason D. Roberts and Zian H. Tseng and Henrik K. Jensen and S.R. Wayne Chen
DOI: 10.1161/CIRCEP.121.010013
09/2021
Variant Reinterpretation in Survivors of Cardiac Arrest With Preserved Ejection Fraction (the Cardiac Arrest Survivors With Preserved Ejection Fraction Registry) by Clinicians and Clinical Commercial Laboratories
Circulation: Genomic and Precision Medicine
Brianna Davies and Kirsten Bartels and Julie Hathaway and Fang Xu and Jason D. Roberts and Rafik Tadros and Martin S. Green and Jeffrey S. Healey and Christopher S. Simpson and Shubhayan Sanatani and Christian Steinberg and Martin Gardner and Paul Angaran and Mario Talajic and Robert Hamilton and Laura Arbour and Colette Seifer and Anne Fournier and Jacqueline Joza and Andrew D. Krahn and Anna Lehman and Zachary W.M. Laksman
DOI: 10.1161/CIRCGEN.120.003235
06/2021
Intermediate-coupled premature ventricular complexes and ventricular tachycardia during exercise recovery
HeartRhythm Case Reports
Christopher O.Y. Li and Sonia Franciosi and Marc W. Deyell and Shubhayan Sanatani
DOI: 10.1016/j.hrcr.2020.11.001
02/2021
Potential overdiagnosis of long QT syndrome using exercise stress and QT stand testing in children and adolescents with a low probability of disease
Journal of Cardiovascular Electrophysiology
Thomas M. Roston and Astrid M. De Souza and Hilary V. Romans and Sonia Franciosi and Kathryn R. Armstrong and Shubhayan Sanatani
DOI: 10.1111/jce.14865
02/2021
To play or not to play? sports participation and shared decision-making in athletes with inherited heart rhythm disorders
British Journal of Sports Medicine
Christopher OY Li and Thomas M Roston and Claire MacEwing and Shubhayan Sanatani
DOI: 10.1136/bjsports-2019-101236
10/2020
Paediatric supraventricular tachycardia patients potentially more at risk of developing psychological difficulties compared to healthy peers
Acta paediatrica (Oslo, Norway : 1992)
Tester MA and Riehm KE and Perry F and Franciosi S and Escudero CA and Maghrabi K and Sneddon P and Sanatani S
DOI: 10.1111/apa.15556
PubMed: 32865825
08/2020
Genotype Predicts Outcomes in Fetuses and Neonates With Severe Congenital Long QT Syndrome
JACC: Clinical electrophysiology
Moore JP and Gallotti RG and Shannon KM and Bos JM and Sadeghi E and Strasburger JF and Wakai RT and Horigome H and Clur SA and Hill AC and Shah MJ and Behere S and Sarquella-Brugada G and Ackerman MJ
DOI: 10.1016/j.jacep.2020.06.001
PubMed: 33213816
08/2020