Simon Whyte

MBBS, FRCA, FRCPC

Investigator and Head, Department of Anesthesia, BC Children's Hospital

I am involved in diverse studies that include defining clinically relevant pharmacodynamic endpoints for drugs used in paediatric anaesthetic and perioperative care, and providing feedback on aspects of quality of intraoperative care, with the common goal of improving patients' experiences & safety.

Examples of such work include: examining the effects of anaesthetic drugs on myocardial repolarization; investigating relationships between anesthetic pharmacodynamics and pharmacogenetics; exploring relationships between intraoperative homeostasis and post-operative outcomes; contributing to and leading the set-up of multi-centre registries.

Academic Affiliations

  • Clinical Associate Professor, , Department of Anesthesiology, Pharmacology & Therapeutics, Faculty of Medicine, University of British Columbia
  • Research Theme: Evidence to Innovation
  • Research Group(s): Clinical Pharmacology; Clinical Practice, Outcomes and Innovation; Clinical and Community Data, Analytics and Informatics

Contact Information

Assistant

Andrew Poznikoff

andrew.poznikoff@phsa.ca

Location

950 West 28th Ave, Vancouver, BC, Canada, V5Z 4H4

Pediatric Airway Management in COVID-19 Patients: Consensus Guidelines from the Society for Pediatric Anesthesia's Pediatric Difficult Intubation Collaborative and the Canadian Pediatric Anesthesia Society

Anesthesia and Analgesia

Matava, C.T. and Kovatsis, P.G. and Lee, J.K. and Castro, P. and Denning, S. and Yu, J. and Park, R. and Lockman, J.L. and Von Ungern-Sternberg, B. and Sabato, S. and Lee, L.K. and Ayad, I. and Mireles, S. and Lardner, D. and Whyte, S. and Szolnoki, J. and Jagannathan, N. and Thompson, N. and Stein, M.L. and Dalesio, N. and Greenberg, R. and McCloskey, J. and Peyton, J. and Evans, F. and Haydar, B. and Reynolds, P. and Chiao, F. and Taicher, B. and Templeton, T. and Bhalla, T. and Raman, V.T. and Garcia-Marcinkiewicz, A. and Glvez, J. and Tan, J. and Rehman, M. and Crockett, C. and Olomu, P. and Szmuk, P. and Glover, C. and Matuszczak, M. and Galvez, I. and Hunyady, A. and Polaner, D. and Gooden, C. and Hsu, G. and Gumaney, H. and Prez-Pradilla, C. and Kiss, E.E. and Theroux, M.C. and Lau, J. and Asaf, S. and Ingelmo, P. and Engelhardt, T. and Hervis, M. and Greenwood, E. and Javia, L. and Disma, N. and Yaster, M. and Fiadjoe, J.E.

DOI: 10.1213/ANE.0000000000004872

Effects of Dexmedetomidine on Myocardial Repolarization in Children Undergoing General Anesthesia: A Randomized Controlled Trial

Anesthesia and analgesia

Grges, M. and Sherwin, E.D. and Poznikoff, A.K. and West, N.C. and Brodie, S.M. and Whyte, S.D.

DOI: 10.1213/ANE.0000000000004135

Integrating intraoperative physiology data into outcome analysis for the ACS Pediatric National Surgical Quality Improvement Program

Paediatric Anaesthesia

Grges, M. and Afshar, K. and West, N. and Pi, S. and Bedford, J. and Whyte, S.D.

DOI: 10.1111/pan.13531

Core Outcome Sets for Pediatric Perioperative Research: An International Stakeholder Engagement Exercise and Consensus Report from the Pediatric Perioperative Outcomes Group

Anesthesiology

Paul A. Stricker and Laszlo Vutskits and Jurgen C. de Graaff and Britta S. von Ungern-Sternberg and Susan M. Goobie and Yun-Xia Zuo and Tania A. Ramos and Heidi M. Meyer and Elsa M. Taylor and Simon D. Whyte and Claudia C. Malic and Piedad C. Echeverry and Wallis T. Muhly and De-Ying Xie and Suellen M. Walker and Cyrus Razavi and Alexandra M. Torborg and Joseph P. Cravero and C. Dean Kurth and Ellen Rawlinson and Lei Yang and Ting Xu and M. Ruth Graham and Rob Seal and Aine Sommerfield and Andrew J. Davidson

DOI: 10.1097/ALN.0000000000005693

11 / 2025

Incidence of cognitive errors in difficult airway management: an inference human factors study from the Pediatric Difficult Intubation Registry

British Journal of Anaesthesia

Bordini, M. and Orsini, L. and Li, S.Y.W. and Olsen, J. and Stein, M.L. and Sarmiento Arg{\"u}ello, L.A. and Hesselink, E.B. and Lee, A.C. and Echeverry, P.C. and Lee, L.K. and O{'}Brien, E.M. and Dalal, P.G. and Hunyady, A. and Whyte, S. and Brooks-Peterson, M. and Garcia-Marcinkiewicz, A.G. and Kovatsis, P. and Peyton, J. and Von Ungern-Sternberg, B.S. and Fiadjoe, J. and Matava, C. and Bruins, B.B. and Stricker, P. and Laverriere, E.K. and Lockman, J.L. and Struyk, B. and Ward, C. and Nishisaki, A. and Kodavatiganti, R. and Daly Guris, R.J. and Sequera-Ramos, L. and Teen, M.S. and Oke, A. and Hsu, G. and Lingappan, A. and Park, R.S. and Egbuta, C. and Battles, R. and Bocanegra, A.D. and Goldfarb, T. and Kiss, E.E. and Szmuk, P. and Mireles, S. and Murray, A. and Jain, R. and Khan, S.A. and Holmes, C. and McCann, A. and Sabato, S. and Dalesio, N. and Greenberg, R. and Desai, S. and Lucero, A. and Schrock, C. and Marsh, J. and Peterson, M.B. and Johnson Lee, A.C. and Bhattacharya, S. and Burjek, N.E. and Rosander, S. and Samba, S. and Jagannathan, N. and Lardner, D. and Crockett, C. and Robertson, S. and Sathyamoorthy, M. and Chao, F. and Patel, J. and Sharma, A. and P{\'e}rez-Pradilla, C. and Singh, N. and Taicher, B. and Sommerfield, D. and Hauser, N. and Lewkowitz-Shpuntoff, H. and Castro, P. and Riveros Perez, N.R. and Vega, E. and Gonz{\'a}lez, A. and Ostermann, P. and Meserve, J. and Lord, C.T. and Leite, F. and Rubin, K. and Valairucha, S. and Ayad, I. and Rehman, M. and Fernandez, A. and Zamora, L. and Tran, T. and Anspach, T. and Shaik, S. and Szolnoki, J. and Mathew, P.J. and Yaddanapudi, S. and Sen, I. and Gupta, A. and Handlogten, K. and Sroka, J.M. and Quintao, V.C. and Weatherall, A.D. and Templeton, T.W. and Flynn, S.G. and Nykiel-Bailey, S. and Padiyath, F. and Matuszczak, M. and Park, R.S. and Olomu, P.N. and Mitchell, K.

DOI: 10.1016/j.bja.2025.04.033

Pharmacodynamic Safety Endpoints for Propofol Anesthesia in Children by Age and Sex: A Multicohort Observational Study

Paediatric Anaesthesia

Moxham, L. and Golam, A. and West, N.C. and G{\"o}rges, M. and Whyte, S.D.

DOI: 10.1111/pan.70031

Comparing videolaryngoscopy and flexible bronchoscopy to rescue failed direct laryngoscopy in children: a propensity score matched analysis of the Pediatric Difficult Intubation Registry

Anaesthesia

Stein, M.L. and Nagle, J.H. and Templeton, T. and Staffa, S.J. and Flynn, S.G. and Bordini, M. and Nykiel-Bailey, S. and Garcia-Marcinkiewicz, A.G. and Padiyath, F. and Matuszczak, M. and Lee, A.C. and Peyton, J.M. and Park, R.S. and von Ungern-Sternberg, B.S. and Olomu, P.N. and Hunyady, A.I. and Matava, C. and Fiadjoe, J.E. and Kovatsis, P.G. and Bruins, B.B. and Stricker, P. and Laverriere, E.K. and Lockman, J.L. and Struyk, B. and Ward, C. and Nishisaki, A. and Kodavatiganti, R. and Daly Guris, R.J. and Sequera-Ramos, L. and Teen, M.S. and Oke, A. and Hsu, G. and Lingappan, A. and Petyon, J.M. and Egbuta, C. and Sarmiento, L. and Battles, R. and Bocanegra, A.D. and Goldfarb, T. and Kiss, E.E. and Szmuk, P. and Mireles, S. and Murray, A. and Whyte, S. and Jain, R. and Khan, S.A. and Holmes, C. and McCann, A. and Sabato, S. and Dalesio, N. and Greenberg, R. and Lucero, A. and Desai, S. and Rosander, S. and Samba, S. and Schrock, C. and Marsh, J. and Peterson, M.B. and Lee, A.C.J. and Bhattacharya, S. and Burjek, N.E. and Jagannathan, N. and Lardner, D. and Crockett, C. and Robertson, S. and Sathyamoorthy, M. and Chiao, F. and Patel, J. and Sharma, A. and Marin, P.E. and P{\'e}rez-Pradilla, C. and Singh, N. and Taicher, B. and Sommerfield, D. and Hauser, N. and Hesselink, E. and Lewkowitz-Shpuntoff, H. and Castro, P. and Perez, N.R.R. and Leite, F. and Vega, E. and Gonz{\'a}lez, A. and Ostermann, P. and Rubin, K. and Meserve, J. and Lord, C. and Valairucha, S. and Dalal, P. and Tran, T. and Anspach, T. and Lee, L.K. and Ayad, I. and Rehman, M. and Fernandez, A. and Zamora, L. and Ravula, N. and Shaik, S. and Szolnoki, J. and Mathew, P.J. and Yaddanapudi, S. and Sen, I. and Gupta, A. and Handlogten, K. and Sroka, J.M. and Quintao, V.C. and Carlos, R.V. and Weatherall, A.D.

DOI: 10.1111/anae.16576

Anesthetic-Sparing Effect of Dexmedetomidine During Total Intravenous Anesthesia for Children Undergoing Dental Surgery: A Randomized Controlled Trial"In Reply

Paediatric Anaesthesia

Lee, V.C.L. and Ridgway, R. and West, N.C. and G{\"o}rges, M. and Whyte, S.D.

DOI: 10.1111/pan.15109

Awake Supraglottic Airway Placement in Pediatric Patients for Airway Obstruction or Difficult Intubation: Insights From an International Airway Registry (PeDI)

Anesthesia and Analgesia

Longacre, M. and Park, R.S. and Staffa, S.J. and Rowland, M.J. and Meserve, J. and Lord, C. and Templeton, T.W. and Garcia-Marcinkiewicz, A.G. and Peyton, J.M. and Fiadjoe, J.E. and Kovatsis, P.G. and Stein, M.L. and Bruins, B.B. and Stricker, P. and Laverriere, E.K. and Lockman, J.L. and Struyk, B. and Ward, C. and Nishisaki, A. and Kodavatiganti, R. and Guris, R.J.D. and Sequera-Ramos, L. and Teen, M.S. and Oke, A. and Hsu, G. and Lingappan, A. and Egbuta, C. and Flynn, S. and Sarmiento, L. and Battles, R. and Bocanegra, A.D. and Goldfarb, T. and Kiss, E.E. and Olomu, P.N. and Szmuk, P. and Mireles, S. and Murray, A. and Whyte, S. and Jain, R. and Khan, S.A. and Matuszczak, M. and Hunyady, A. and Holmes, C. and Mccann, A. and Sabato, S. and Matava, C. and Dalesio, N. and Greenberg, R. and Lucero, A. and Desai, S. and Tennessee, N. and Rosander, S. and Samba, S. and Schrock, C. and Nykiel-Bailey, S. and Marsh, J. and Brooks Peterson, M. and Johnson Lee, A.C. and Bhattacharya, S. and Burjek, N.E. and Jagannathan, N. and Lardner, D. and Crockett, C. and Robertson, S. and Sathyamoorthy, M. and Chiao, F. and Patel, J. and Sharma, A. and Echeverry Marin, P. and P{\'e}rez-Pradilla, C. and Singh, N. and Taicher, B. and Von Ungern-Sternberg, B.S. and Sommerfield, D. and Hauser, N. and Hesselink, E. and Lewkowitz-Shpuntoff, H. and Castro, P. and Riveros Perez, N.R. and Leite, F. and Vega, E. and Gonz{\'a}lez, A. and Ostermann, P. and Rubin, K. and Lee, A. and Valairucha, S. and Dalal, P. and Tran, T. and Anspach, T. and Lee, L.K. and Ayad, I. and Rehman, M. and Fernandez, A. and Zamora, L. and Ravula, N. and Shaik, S. and Szolnoki, J. and Mathew, P.J. and Yaddanapudi, S. and Sen, I. and Gupta, A. and Handlogten, K. and Sroka, J.M. and Caldeira Quintao, V. and Vieira Carlos, R.

DOI: 10.1213/ANE.0000000000006959

Airway management in the paediatric difficult intubation registry: a propensity score matched analysis of outcomes over time

eClinicalMedicine

Stein, M.L. and Sarmiento Argello, L.A. and Staffa, S.J. and Heunis, J. and Egbuta, C. and Flynn, S.G. and Khan, S.A. and Sabato, S. and Taicher, B.M. and Chiao, F. and Bosenberg, A. and Lee, A.C. and Adams, H.D. and von Ungern-Sternberg, B.S. and Park, R.S. and Peyton, J.M. and Olomu, P.N. and Hunyady, A.I. and Garcia-Marcinkiewicz, A. and Fiadjoe, J.E. and Kovatsis, P.G. and Bruins, B. and Stricker, P. and Laverriere, E. and Lockman, J.L. and Struyk, B. and Ward, C. and Nishisaki, A. and Kodavatiganti, R. and Guris, R.D. and Sequera-Ramos, L. and Teen, M. and Oke, A. and Hsu, G. and Lingappan, A. and Battles, R. and Bocanegra, A. and Goldfarb, T. and Kiss, E. and Szmuk, P. and Mireles, S. and Murray, A. and Whyte, S. and Jain, R. and Matuszczak, M. and Holmes, C. and McCann, A. and Matava, C. and Dalesio, N. and Greenberg, R. and Lucero, A. and Desai, S. and Rosander, S. and Samba, S. and Schrock, C. and Nykiel-Bailey, S. and Marsh, J. and Peterson, M.B. and Lee, A. and Bhattacharya, S. and Burjek, N. and Jagannathan, N. and Lardner, D. and Crockett, C. and Robetson, S. and Patel, J. and Sharma, A. and Templeton, T. and Marn, P.E. and Prez-Pradilla, C. and Singh, N. and Sommerfield, D. and Hauser, N. and Hesselink, E. and Lewkowitz-Shpuntoff, H. and Castro, P. and Riveros Perez, N.R. and Vega, E. and Gonzlez, A. and Ostermann, P. and Rubin, K. and Meserve, J. and Lord, C. and Lee, A. and Valairucha, S. and Dalal, P. and Tran, T. and Anspach, T. and Lee, L.K. and Ayad, I. and Rehman, M. and Fernandez, A. and Zamora, L. and Ravula, N. and Shaik, S. and Szolnoki, J. and Mathew, P. and Yaddanapudi, S. and Sen, I. and Gupta, A. and Handlogten, K. and Sroka, J.M. and Quinto, V.C. and Carlos, R.V. and Leite, F.

DOI: 10.1016/j.eclinm.2024.102461

Anesthetic-sparing effect of dexmedetomidine during total intravenous anesthesia for children undergoing dental surgery: A randomized controlled trial

Paediatric Anaesthesia

Lee, V.C.L. and Ridgway, R. and West, N.C. and Grges, M. and Whyte, S.D.

DOI: 10.1111/pan.14987

Pediatric anesthesia in North America

Paediatric Anaesthesia

Srinivasan, I. and Whyte, S. and Bailey, K. and Antrobus, T. and Hinkson-LaCorbinire, K. and Martin, T.W. and Cravero, J.P. and Mason, L.

DOI: 10.1111/pan.14872

A survey of practice in the anesthetic management of adolescent idiopathic scoliosis spine fusion by the North American Pediatric Spine Anesthesiologists Collaborative

Paediatric Anaesthesia

Gilbertson, L.E. and Muhly, W.T. and Montana, M.C. and Chidambaran, V. and DiCindio, S. and Sadacharam, K. and Wilder, R.T. and Whyte, S.D. and Hifko, A. and Sponseller, P.D. and Frankville, D.D.

DOI: 10.1111/pan.14895

An Individualized Postoperative Pain Risk Communication Tool for Use in Pediatric Surgery: Co-Design and Usability Evaluation (Preprint)

Michael D Wood and Nicholas C West and Christina Fokkens and Ying Chen and Kent C Loftsgard and Krystal Cardinal and Simon D Whyte and Elodie Portales-Casamar and Matthias Grges

DOI: 10.2196/preprints.46785

02 / 2023

Anesthesia and neurodevelopment after 20 years: where are we now and where to next?,Anesthsie et neurodveloppement, 20 ans aprs: regard actuel et perspectives davenir

Canadian Journal of Anesthesia

Bailey, K.M. and Whyte, S.D.

DOI: 10.1007/s12630-022-02352-8

Difficult or impossible facemask ventilation in children with difficult tracheal intubation: a retrospective analysis of the PeDI registry

British Journal of Anaesthesia

Garcia-Marcinkiewicz, A.G. and Lee, L.K. and Haydar, B. and Fiadjoe, J.E. and Matava, C.T. and Kovatsis, P.G. and Peyton, J. and Stein, M.L. and Park, R. and Taicher, B.M. and Templeton, T.W. and Bruins, B.B. and Stricker, P. and Laverriere, E.K. and Lockman, J.L. and Struyk, B. and Ward, C. and Nishisaki, A. and Kodavatiganti, R. and Daly Guris, R.J. and Sequera-Ramos, L. and Teen, M.S. and Oke, A. and Hsu, G. and Lingappan, A. and Egbuta, C. and Flynn, S. and Sarmiento, L. and Goldfarb, T. and Kiss, E.E. and Olomu, P.N. and Szmuk, P. and Mireles, S. and Murray, A. and Whyte, S. and Jain, R. and Matuszczak, M. and Hunyady, A. and Bosenberg, A. and Tham, S. and Low, D. and Holmes, C. and Sabato, S. and Dalesio, N. and Greenberg, R. and Lucero, A. and Reynolds, P. and Lewis, I. and Schrock, C. and Nykiel-Bailey, S. and Starker, E. and Szolnoki, J. and Brooks-Peterson, M. and Bhattacharya, S. and Burjek, N.E. and Jagannathan, N. and Lardner, D. and Watkins, S. and Crockett, C. and Moore, J. and Robertson, S. and Sathyamoorthy, M. and Chiao, F. and Patel, J. and Sharma, A. and Echeverry Marin, P. and P{\'e}rez-Pradilla, C. and Singh, N. and von Ungern-Sternberg, B.S. and Sommerfield, D. and Bilen-Rosas, G. and Lewkowitz-Shpuntoff, H. and Castro, P. and Riveros Perez, N.R. and de Graaff, J.C. and Vega, E. and Gonz{\'a}lez, A. and Ostermann, P. and Rubin, K. and Lord, C.T. and Lee, A. and Heitmiller, E. and Valairucha, S. and Dalal, P. and Tran, T. and Ayad, I. and Rehman, M. and Fernandez, A. and Zamora, L. and Ravula, N. and Shaik, S.

DOI: 10.1016/j.bja.2023.02.035

Efficacy of a hybrid technique of simultaneous videolaryngoscopy with flexible bronchoscopy in children with difficult direct laryngoscopy in the Pediatric Difficult Intubation Registry

Anaesthesia

Stein, M.L. and Park, R.S. and Kiss, E.E. and Adams, H.D. and Burjek, N.E. and Peyton, J. and Szmuk, P. and Staffa, S.J. and Fiadjoe, J.E. and Kovatsis, P.G. and Olomu, P.N. and Bruins, B.B. and Stricker, P. and Laverriere, E.K. and Garcia-Marcinkiewicz, A.G. and Lockman, J.L. and Struyk, B. and Ward, C. and Nishisaki, A. and Kodavatiganti, R. and Guris, R.J.D. and Sequera-Ramos, L. and Teen, M.S. and Oke, A. and Hsu, G. and Goldfarb, T. and Lingappan, A. and Egbuta, C. and Flynn, S. and Sarmiento, L. and Mireles, S. and Murray, A. and Whyte, S. and Jain, R. and Matuszczak, M. and Hunyady, A. and Holmes, C. and Sabato, S. and Matava, C. and Dalesio, N. and Greenberg, R. and Lucero, A. and Reynolds, P. and Lewis, I. and Haydar, B. and Schrock, C. and Nykiel-Bailey, S. and Marsh, J. and Peterson, M.B. and Lee, A.C.J. and Bhattacharya, S. and Jagannathan, N. and Lardner, D. and Crockett, C. and Robertson, S. and Sathyamoorthy, M. and Chiao, F. and Patel, J. and Sharma, A. and Templeton, T.W. and Marin, P.E. and P{\'e}rez-Pradilla, C. and Singh, N. and Taicher, B. and von Ungern-Sternberg, B.S. and Sommerfield, D. and Hauser, N. and Hesselink, E. and Lewkowitz-Shpuntoff, H. and Castro, P. and Perez, N.R.R. and Vega, E. and Gonz{\'a}lez, A. and Ostermann, P. and Rubin, K. and Meserve, J. and Lord, C. and Lee, A. and Heitmiller, E. and Valairucha, S. and Dalal, P. and Tran, T. and Lee, L.K. and Ayad, I. and Rehman, M. and Fernandez, A. and Zamora, L. and Ravula, N. and Shaik, S.

DOI: 10.1111/anae.16049

An Individualized Postoperative Pain Risk Communication Tool for Use in Pediatric Surgery: Co-Design and Usability Evaluation

JMIR Pediatrics and Parenting

Wood, M.D. and West, N.C. and Fokkens, C. and Chen, Y. and Loftsgard, K.C. and Cardinal, K. and Whyte, S.D. and Portales-Casamar, E. and G{\"o}rges, M.

DOI: 10.2196/46785

Identification of Requirements for a Postoperative Pediatric Pain Risk Communication Tool: Focus Group Study With Clinicians and Family Members (Preprint)

Michael D Wood and Kim Correa and Peijia Ding and Rama Sreepada and Kent C Loftsgard and Isabel Jordan and Nicholas C West and Simon D Whyte and Elodie Portales-Casamar and Matthias Grges

DOI: 10.2196/preprints.37353

02 / 2022

A pharmacogenomic investigation of the cardiac safety profile of ondansetron in children and pregnant women

Biomedicine and Pharmacotherapy

Drgemller, B.I. and Wright, G.E.B. and Trueman, J. and Shaw, K. and Staub, M. and Chaudhry, S. and Miao, F. and Higginson, M. and Groeneweg, G.S.S. and Brown, J. and Magee, L.A. and Whyte, S.D. and West, N. and Brodie, S.M. and Jong, G.?. and Israels, S. and Berger, H. and Ito, S. and Rassekh, S.R. and Sanatani, S. and Ross, C.J.D. and Carleton, B.C.

DOI: 10.1016/j.biopha.2022.112684

Blood pressure nomograms for children undergoing general anesthesia, stratified by age and anesthetic type, using data from aretrospective cohort at a tertiary pediatric center

Journal of Clinical Monitoring and Computing

Hillgruber, R.J. and Lutskov, P. and West, N.C. and Whyte, S. and Grges, M.

DOI: 10.1007/s10877-022-00811-7

Identification of Requirements for a Postoperative Pediatric Pain Risk Communication Tool: Focus Group Study With Clinicians and Family Members

JMIR Pediatrics and Parenting

Wood, M.D. and Correa, K. and Ding, P. and Sreepada, R. and Loftsgard, K.C. and Jordan, I. and West, N.C. and Whyte, S.D. and Portales-Casamar, E. and G{\"o}rges, M.

DOI: 10.2196/37353

Safety of antifibrinolytics in 6583 pediatric patients having craniosynostosis surgery: A decade of data reported from the multicenter Pediatric Craniofacial Collaborative Group

Paediatric Anaesthesia

King, M.R. and Staffa, S.J. and Stricker, P.A. and P{\'e}rez-Pradilla, C. and Nelson, O. and Benzon, H.A. and Goobie, S.M. and Abruzzese, C. and Asmal, I. and Bailey, K. and Barker, N. and Bhandari, A. and Beethe, A. and Binstock, W. and van den Bosch, C. and Bradford, V. and Bradley, J. and Bryan, K. and Brzenski, A. and Budac, S. and Busso, V. and de Castro, A. and Castro-Frenzel, K. and Chhabada, S. and Chiao, F. and Ching, J. and Cladis, F. and Claypool, D. and Collins, M. and Correll, L. and Costandi, A. and Dabek, R. and Dalesio, N. and Downard, M. and Echeverry, P. and Edala, T. and Edwards, C. and Ellison, P.R. and Enicker, B. and Falcon, R. and Fernandez, A. and Fernandez, P. and Fiadjoe, J. and Franzen, M. and Gangadharan, M. and Glover, C. and Gosman, A. and Governale, L. and Grivoyannis, A. and Grap, S. and Gries, H. and Griffin, A. and Hajduk, J. and Haas, T. and Hansen, J. and Hetmaniuk, M. and Homi, H.M. and Hsieh, H. and Hsieh, V. and Huang, H. and Ingelmo, P. and Ivanova, I. and Jain, R. and Kamel, G. and Kanmanthreddy, S. and Kars, M. and Koller, J. and Kowalczyk-Derderian, C. and Kugler, J. and Labovsky, K. and Lakheeram, I. and Lazar, A. and Lee, A. and Lee, J. and Madaree, A. and Malviya, S. and Martinez, J.L. and Mason, A. and Medellin, E. and Mehta, V. and Meier, P.M. and Levy, H.M. and Mueller, M. and Muhly, W.T. and Muldowney, B. and Nause-Osthoff, R. and Nelson, J. and Nicholson, J. and Nguyen, K.-P. and Nguyen, T. and Owens-Stubblefield, M. and Pankratz, M. and Parekh, U.R. and Parikh, M. and Patel, J. and Patel, R. and Patel, V. and Petersen, T. and Post, J. and Poteet-Schwartz, K. and Puglia, M.P. and Reddy, S.K. and Reid, R. and Ricketts, K. and McCormick, M.R. and Ryan, L. and Sbrollini, K. and Seidman, P. and Seubert, C. and Salik, I. and Singh, D.J. and Singhal, N.R. and Skitt, R. and Soneru, C. and Sorial, E. and Starker, E. and Stubbeman, B. and Sunder, R. and Sung, W. and Syed, T. and Szmuk, P. and Taicher, B.M. and Taylor, J. and Taylor, K. and Thompson, D. and Titler, S.S. and Ungar-Kastner, G. and Whyte, S. and Wong, A. and Wong, K. and Yates, H. and Zamora, L.

DOI: 10.1111/pan.14540

Sedation versus General Anesthesia for Tracheal Intubation in Children with Difficult Airways: A Cohort Study from the Pediatric Difficult Intubation Registry

Anesthesiology

Sequera-Ramos, L. and Laverriere, E.K. and Garcia-Marcinkiewicz, A.G. and Zhang, B. and Kovatsis, P.G. and Fiadjoe, J.E. and Lardner, D. and Von Ungern-Sternberg, B.S. and Sommerfield, D. and Holmes, C. and Sabato, S. and Ravula, N. and Jette, C. and Mireles, S. and Matava, C. and Whyte, S. and Vega, E. and Yang, L. and Echeverry-Marin, P. and P{\'e}rez-Pradilla, C. and Jagannathan, N. and Burjek, N.E. and Polaner, D. and Starker, E. and Szolnoki, J. and Brooks-Peterson, M. and Lee, A. and Heitmiller, E. and Rehman, M. and Fernandez, A. and Meserve, J. and Lord, C. and McCloskey, J. and Dalesio, N. and Koka, R. and Greenberg, R. and Park, R. and Peyton, J. and Stein, M.L. and Egbuta, C. and Flynn, S. and Bhattacharya, S. and Reynolds, P. and Lewis, I. and Haydar, B. and Sarmiento, L. and Richtsfeld, M. and Belani, K. and Robertson, S. and Sathyamoorthy, M. and Schrock, C. and De Graaff, J.C. and Soneru, C. and Singh, N. and Chiao, F. and Taicher, B. and Templeton, T. and Castro, P. and Perez, N.R.R. and Raman, V.T. and Beltran, R. and Bhalla, T. and Bruins, B.B. and Stricker, P. and Lockman, J.L. and Struyk, B. and Ward, C. and Nishisaki, A. and Kodavatiganti, R. and Guris, R.J.D. and Teen, M.S. and Mar{\'i}n, P.C.E. and Watkins, S. and Crockett, C. and Moore, J. and Goldfarb, T. and Olomu, P. and Szmuk, P. and Hopkins, P. and Glover, C. and Nguyen, K. and Shaw, T.L. and Olutoye, O. and Jain, R. and Matuszczak, M. and Hunyady, A. and Bosenberg, A. and Tham, S. and Low, D. and Bilen-Rosas, G. and Fehr, J. and Lee, L.K. and Ayad, I. and Patel, R. and Gooden, C.

DOI: 10.1097/ALN.0000000000004353

Association of dexmedetomidine with recovery room and hospital discharge times: A retrospective cohort analysis

Pediatric Anesthesia

Nicholas West and Matthias Grges and Andrew Poznikoff and Simon Whyte and Stephan Malherbe

DOI: 10.1111/pan.14257

11 / 2021

A survey of the global impact of COVID-19 on the practice of pediatric anesthesia: A study from the pediatric anesthesia COVID-19 Collaborative Group

Paediatric Anaesthesia

Soneru, C.N. and Fernandez, A.M. and Bradford, V. and Staffa, S.J. and Raman, V.T. and Cravero, J. and Zurakowski, D. and Meier, P.M. and Balakrishnan, S. and Bansal, V. and Torres, A.B. and Beethe, A. and Benzon, H.A. and Bhandari, A. and Bocanegra, A. and Bould, D. and Peterson, M.B. and Brzenski, A. and Busso, V. and Cain, J.G. and Cassidy, M. and Cheon, E.C. and Chhabada, S. and Correll, L.R. and Dalesio, N.M. and Davidson, A. and Derderian, C. and Dhumak, V. and Disma, N. and D'Mello, A. and Echeverry, P. and Ellison, P.R. and Erb, T. and Fajardo, A. and Falcon, R.J. and Frugoni, B. and Garca, J. and Giraldo, O.L. and Glover, C.D. and Goeller, J. and Goobie, S.M. and Gooch, I. and Granados, L.M. and Grivoyannis, A. and Guruswamy, V. and Hesselink, E. and Hobbs, J. and Hunyady, A. and Jain, R. and Jorge-Reynolds, L. and Kato, M.A. and King, M.R. and Kitzman, J. and Koh, J. and Lester, A. and Lorinc, A. and Lozano, C. and Manupipatpong, K. and Matava, C. and McLuckie, D. and Merchant, K. and Levy, H.M. and Muldowney, B.L. and Navarro, J.A. and Nelson, J. and Patel, A. and Patel, R. and Ravula, N. and Reddy, D. and Reddy, S.K. and McCormick, M.R. and Roque, R. and Rosen, D. and Beel, E.R. and Rothschild, L. and Sarmiento, L. and Shadrina, A. and Shaw, R. and Sheth, M. and Simpao, A.F. and Singh, N. and Smith, T.E. and Soria, C. and Szmuk, P. and Taicher, B.M. and Tan, G.M. and Teng, H. and Edala, T. and Tighe, N. and Tom, S. and Trujillo, A. and Vishneski, S.R. and Vivas, J.P. and Samek, A.V. and von Ungern-Sternberg, B.S. and Whyte, S. and Wilder, R.T.

DOI: 10.1111/pan.14174

A comparison of videolaryngoscopy using standard blades or non-standard blades in children in the Paediatric Difficult Intubation Registry

British Journal of Anaesthesia

Peyton, J. and Park, R. and Staffa, S.J. and Sabato, S. and Templeton, T.W. and Stein, M.L. and Garcia-Marcinkiewicz, A.G. and Kiss, E. and Fiadjoe, J.E. and von Ungern-Sternberg, B. and Chiao, F. and Olomu, P. and Zurakowski, D. and Kovatsis, P.G. and Sommerfield, D. and Holmes, C. and Ravula, N. and Jette, C. and Mireles, S. and Matava, C. and Whyte, S. and Vega, E. and Yang, L. and Echeverry-Marin, P. and Perez-Pradilla, C. and Starker, E. and Zieg, J. and Szolnoki, J. and Lee, A. and Heitmiller, E. and Rehman, M. and Zamora, L. and Fernandez, A. and Meserve, J. and Bhattacharya, S. and Reynolds, P. and Lewis, I. and Haydar, B. and Therrian, M. and Sarmiento, L. and Richtsfeld, M. and Belani, K. and Robertson, S. and Sathyamoorthy, K. and Schrock, C. and de Graaff, J. and Soneru, C. and Singh, N. and Taicher, B. and Castro, P. and Riveros Perez, N.R. and Stricker, P. and Lockman, J.L. and Galvez, J. and Isserman, R. and Struyk, B. and Ward, C. and Hsu, G. and Nishisaki, A. and Kodavatiganti, R. and Ramos, L.S. and Scheu, E. and Bruins, B. and Goldfarb, T. and Szmuk, P. and Jain, R. and Matuszczak, M. and Polaner, D. and Hunyady, A. and Bosenberg, A. and Tham, S. and Low, D. and Rosas, G.B. and Lee, L.K. and Iyah, I. and Dalesio, N. and Greenberg, R.

DOI: 10.1016/j.bja.2020.08.010

The Effect of Carbetocin Dose on Transmural Dispersion of Myocardial Repolarization in Healthy Parturients Scheduled for Elective Cesarean Delivery Under Spinal Anesthesia: A Prospective, Randomized Clinical Trial

Anesthesia and Analgesia

Clunies-Ross, N. and Roston, T.M. and Taylor, J. and Whyte, S. and Albert, A. and Grges, M. and Chau, A.

DOI: 10.1213/ANE.0000000000004712

Caudal and Intravenous Anesthesia Without Airway Instrumentation for Laparoscopic Inguinal Hernia Repair in Infants: A Case Series

A&A practice

Krishnan, P. and Whyte, S.D. and Baird, R. and Malherbe, S.

DOI: 10.1213/XAA.0000000000001251

A systematic review of outcomes reported in pediatric perioperative research: A report from the Pediatric Perioperative Outcomes Group

Paediatric Anaesthesia

Muhly, W.T. and Taylor, E. and Razavi, C. and Walker, S.M. and Yang, L. and de Graaff, J.C. and Vutskits, L. and Davidson, A. and Zuo, Y. and Prez-Pradilla, C. and Echeverry, P. and Torborg, A.M. and Xu, T. and Rawlinson, E. and Subramanyam, R. and Whyte, S. and Seal, R. and Meyer, H.M. and Yaddanapudi, S. and Goobie, S.M. and Cravero, J.P. and Keaney, A. and Graham, M.R. and Ramos, T. and Stricker, P.A. and Malic, C.C. and von Ungern-Sternberg, B.S. and Shivera, T. and Yu, G.

DOI: 10.1111/pan.13981

Effects of Dexmedetomidine on Blood Glucose and Serum Potassium Levels in Children Undergoing General Anesthesia: A Secondary Analysis of Safety Endpoints During a Randomized Controlled Trial

Anesthesia and analgesia

Grges, M. and Poznikoff, A.K. and West, N.C. and Brodie, S.M. and Brant, R.F. and Whyte, S.D.

DOI: 10.1213/ANE.0000000000004154

Audit and feedback: to tell or not to tell? That is not the question,Audit et rtroaction: dire ou ne pas dire? Telle nest pas la question

Canadian Journal of Anesthesia

Whyte, S.

DOI: 10.1007/s12630-018-1206-z

Using physiological monitoring data for performance feedback: an initiative using thermoregulation metrics,Utilisation des donnes de monitorage physiologique pour les rtroactions sur la performance: une initiative base sur les mesures de la thermorgulation

Canadian Journal of Anesthesia

Grges, M. and West, N.C. and Whyte, S.D.

DOI: 10.1007/s12630-016-0762-3

Preoperative warming and undesired surgical and anesthesia outcomes in pediatric spinal surgery"a retrospective cohort study

Paediatric Anaesthesia

Grges, M. and West, N.C. and Cheung, W. and Zhou, G. and Miyanji, F. and Whyte, S.D.

DOI: 10.1111/pan.12939

Changes in QTc associated with a rapid bolus dose of dexmedetomidine in patients receiving TIVA: A retrospective study

Paediatric Anaesthesia

Grges, M. and Whyte, S.D. and Sanatani, S. and Dawes, J. and Montgomery, C.J. and Ansermino, J.M.

DOI: 10.1111/pan.12780

The safety of modern anesthesia for children with long QT syndrome

Anesthesia and Analgesia

Whyte, S.D. and Nathan, A. and Myers, D. and Watkins, S.C. and Kannankeril, P.J. and Etheridge, S.P. and Andrade, J. and Collins, K.K. and Law, I.H. and Hayes, J. and Sanatani, S.

DOI: 10.1213/ANE.0000000000000389

ACS national surgical quality improvement program: Targeting quality improvement in Canadian pediatric surgery

Journal of Pediatric Surgery

Skarsgard, E.D. and Bedford, J. and Chan, T. and Whyte, S. and Afshar, K.

DOI: 10.1016/j.jpedsurg.2014.02.047

Paediatric cases

A Surgeon's Guide to Anaesthesia and Peri-Operative Care

Whyte, S. and Butterworth, S.

DOI: 10.1017/CBO9781139628808.016

Paediatrics

Surgeon's Guide to Anaesthesia and Perioperative Care

SD Whyte & SA Butterworth. Chapter 15: Paediatrics. In: Sturgess, Davies & Valchanov, ed. Surgeons Guide to Anaesthesia and Perioperative Care. Cambridge University Press 2014.

A retrospective audit to examine the effectiveness of preoperative warming on hypothermia in spine deformity surgery patients

Paediatric Anaesthesia

Grges, M. and Ansermino, J.M. and Whyte, S.D.

DOI: 10.1111/pan.12204

Usability and performance characteristics of the pediatric air-Q intubating laryngeal airway

Canadian Journal of Anesthesia

Whyte, S.D. and Cooke, E. and Malherbe, S.

DOI: 10.1007/s12630-013-9918-6

Anaesthesia for elective ear, nose and throat surgery in children

Anaesthesia and Intensive Care Medicine

Brown, Z. and Whyte, S.

DOI: 10.1016/j.mpaic.2012.02.010

Normal Tp-e values in children

Anesthesia and Analgesia

Sanatani, S. and Whyte, S.

DOI: 10.1213/ANE.0b013e31823554ac

Dexmedetomidine for co-analgesia in chemotherapy-induced severe enterocolitis

Paediatric Anaesthesia

Winton, P. and Whyte, E. and Reimer, E.J. and Davis, J. and Whyte, S.

DOI: 10.1111/j.1460-9592.2011.03575.x

Intubation via the intubating laryngeal airway in two pediatric patients with predicted difficult airways

Paediatric Anaesthesia

Peiris, K. and Traynor, M. and Whyte, S.

DOI: 10.1111/j.1460-9592.2009.03222.x

Total intravenous anesthesia and spontaneous respiration for airway endoscopy in children - A prospective evaluation

Paediatric Anaesthesia

Malherbe, S. and Whyte, S. and Singh, P. and Amari, E. and King, A. and Mark Ansermino, J.

DOI: 10.1111/j.1460-9592.2010.03290.x

The effects of droperidol and ondansetron on dispersion of myocardial repolarization in children

Paediatric Anaesthesia

Mehta, D. and Sanatani, S. and Whyte, S.D.

DOI: 10.1111/j.1460-9592.2010.03408.x

Perioperative fluid and electrolyte balance in children

Anaesthesia and Intensive Care Medicine

Whyte, S.D.

DOI: 10.1016/j.mpaic.2008.10.006

Editorial

Current Anaesthesia and Critical Care

Whyte, S.D.

DOI: 10.1016/j.cacc.2008.09.002

The effect of propofol concentration on dispersion of myocardial repolarization in children

Anesthesia and Analgesia

Hume-Smith, H.V. and Sanatani, S. and Lim, J. and Chau, A. and Whyte, S.D.

DOI: 10.1213/ane.0b013e3181815ce3

A comparison of the effect on dispersion of repolarization of age-adjusted MAC values of sevoflurane in children

Anesthesia and Analgesia

Whyte, S.D. and Sanatani, S. and Lim, J. and Booker, P.D.

DOI: 10.1213/01.ane.0000252417.23986.6e

Anesthetic considerations in the management of Wilms' tumor

Paediatric Anaesthesia

Whyte, S.D. and Mark Ansermino, J.

DOI: 10.1111/j.1460-9592.2006.01866.x

Torsades de pointes with sevoflurane [6]

Paediatric Anaesthesia

Whyte, S.D. and Sanatani, S. and Booker, P.D.

DOI: 10.1111/j.1460-9592.2006.01994.x

The effects of propofol and sevoflurane on the QT interval and transmural dispersion of repolarization in children

Anesthesia and Analgesia

Whyte, S.D. and Booker, P.D. and Buckley, D.G.

DOI: 10.1213/01.ANE.0000140781.18391.41

Anaesthesia and transmural dispersion of repolarisation in children

Canadian Journal of Anesthesia

Whyte, S.D. and Booker, P.D. and Buckley, D.G.

DOI: 10.1007/BF03023094

Bispectral index during isoflurane anesthesia in pediatric patients

Anesthesia and Analgesia

Whyte, S.D. and Booker, P.D.

DOI: 10.1213/01.ANE.0000117223.84646.36

Newborn life support and the anaesthetist

Current Anaesthesia and Critical Care

Whyte, S.

DOI: 10.1016/j.cacc.2004.08.005

Usefulness of the Minute Ventilation Test in Predicting Successful Extubation in Newborn Infants: A Randomized Controlled Trial

Journal of Perinatology

Lorna M Gillespie and Simon D White and Sunil K Sinha and Steven M Donn

DOI: 10.1038/sj.jp.7210886

04 / 2003

Monitoring the depth of anaesthesia

British Journal of Anaesthesia

1. Whyte SD, Booker PD. Monitoring the depth of anaesthesia. Br J Anaesth CEPD Reviews 2003; 3(4): 106-10.

Long QT syndrome and anaesthesia

British Journal of Anaesthesia

Booker, P.D. and Whyte, S.D. and Ladusans, E.J.

DOI: 10.1093/bja/aeg061

Monitoring depth of anaesthesia by EEG

Continuing Education in Anaesthesia, Critical Care and Pain

Whyte, S.D. and Booker, P.D.

DOI: 10.1093/bjacepd/mkg106

Paediatric applications of concentration-orientated anaesthesia

Best Practice and Research: Clinical Anaesthesiology

Booker, P.D. and Whyte, S.D.

DOI: 10.1053/bean.2000.0138

Premedication before intubation in UK neonatal units

Archives of Disease in Childhood: Fetal and Neonatal Edition

Whyte, S. and Birrell, G. and Wyllie, J.

DOI: 10.1136/fn.82.1.F38

Neonatal resuscitation - A practical assessment

Resuscitation

Whyte, S.D. and Sinha, A.K. and Wyllie, J.P.

DOI: 10.1016/S0300-9572(98)00143-9

Paediatric basic life support: A practical assessment

Resuscitation

Whyte, S.D. and Wyllie, J.P.

DOI: 10.1016/S0300-9572(99)00056-8

Patient-controlled analgesia: Epidural fentanyl and i.v. morphine compared after Caesarean section

British Journal of Anaesthesia

Cooper, D.W. and Saleh, U. and Taylor, M. and Whyte, S. and Ryall, D. and Kokri, M.S. and Desira, W.R. and Day, H. and McArthur, E.

DOI: 10.1093/bja/82.3.366

Inability to adhere to current european neonatal resuscitation guidelines

Pediatric Research

Whyte, S.D. and Sinha, A.J. and Wyllie, J.P.

DOI: 10.1203/00006450-199809000-00110

CANadian PAediatric National Difficult Airway Registry (CANPANDA)

The first stage of this work was to establish a local difficult intubation database in our operating rooms. This went live in July 2017. The next stage was to expand the database to allow other Canadian tertiary paediatric anaesthesia departments to contribute data. This went live in May 2021.

G2ED50

This study measures 4 pharmacodynamic endpoints for progressively increasing depth of anaesthesia during induction, in children undergoing total intravenous anaesthesia. The goal is to better define the safety margin between loss of consciousness and cessation of breathing, in children of different ages, sex and - novelly - genetic ancestry. We'll undertake pharmacogenomic analyses for single nucleotide polymorphisms in potential anaesthetic receptor targets, to investigate any correlation between pharmacodynamic and pharmacogenomic variability.

Grants

2019 CRSU. Genetic ancestral differences in pharmacodynamic safety endpoints with propofol anaesthesia in children

2019 BCCHRI E2i. Genetic ancestral differences in pharmacodynamic safety endpoints with propofol anaesthesia in children

2016-2017 Evidence to Innovation Seed Grant

“BCCH Pediatric Anesthesia Difficult Airway Database

A Quality Improvement Initiative to Improve Safety in Patients with Difficult Airways”

Honours & Awards

Child & Family Research Institute Innovations in Acute Care & Technology Trainee Clinical Investigator Seed Grant - Project

"The effect of preoperative warming on surgical complications in pediatric scoliosis repair," $5,000. 2013.

Child & Family Research Institute Pharmaceutical Outcomes and Policy Innovations - Project

"5-HT3 Antagonists and Cardiac Safety," $42,667. 2014/15.

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