For the latest publications, please visit Dr. Turvey’s ORCID profile.
Patrick DM^, Sbihi H^, Dai DLY^, Al Mamun A^, Rasali D, Rose C, Marra F, Boutin RCT, Petersen C, Stiemsma LT, Winsor GL, Brinkman FSL, Kozyrskyj AL, Azad MB, Becker AB, Mandhane PJ, Moraes TJ, Sears MR, Subbarao P, Finlay BB, Turvey SE (2020). Decreasing antibiotic use, the gut microbiota, and asthma incidence in children: evidence from population-based and prospective cohort studies. Lancet Respir Med. PMID: 32220282
^These authors contributed equally to this paper.
Lu HY, Sharma M, Biggs C, Huang Y, Shopsowitz KE, Frosk P, Priatel JJ, Rubin TS, Turvey SE (2018). The importance of functional validation after next generation sequencing: evaluation of a novel CARD11 variant. Pediatr Allergy Immunol. PMID: 29808493
Tang AC, Rahavi SM, Fung SY, Lu HY, Yang H, Lim CJ, Reid GS, Turvey SE (2018). Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1β production. Cell Death & Disease 9:162. PMID: 29415982
Biggs CM, Haddad E, Issekutz TB, Roifman CM, Turvey SE (2017). Newborn screening for severe combined immunodeficiency: a primer for clinicians. CMAJ 189:E1551-1557. PMID: 29255099
Arrieta MC, Arévalo A, Stiemsma L, Dimitriu P, Chico ME, Loor S, Vaca M, Boutin RCT, Morien E, Jin M, Turvey SE, Walter J, Parfrey LW, Cooper PJ, Finlay B (2017). Associations between infant fungal and bacterial dysbiosis and childhood atopic wheeze in a nonindustrialized setting. J Allergy Clin Immunol. PMID: 29241587
Yang H, Fung SY, Bao A, Li Q, Turvey SE (2017). Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-Like Receptor Signaling. J Vis Exp:125, e56075. PMID: 28784964
Biggs CM, Lu HY, Turvey SE (2017). Monogenic immune disorders and severe atopic disease. Nature Genetics 49: 1162-1163. PMID: 28747751
Del Bel KL^, Ragotte RJ^, Saferali A, Lee S, Vercauteren SM, Mostafavi SA, Schreiber RA, Prendiville JS, Phang MS, Halparin J, Au N, Dean JM, Priatel JJ, Jewels E, Junker AK, Rogers PC, Seear M, McKinnon ML*, Turvey SE* (2017). JAK1 gain-of-function causes an autosomal dominant immune dysregulatory and hypereosinophilic syndrome. J Allergy Clin Immunol 139(6):2016-2020. PMID: 28111307
^These authors contributed equally to this paper. *Co-corresponding authors.
Ragotte RJ^, Dhanrajani A^, Pleydell-Pearce J, Del Bel KL, Tarailo-Graovac M, van Karnebeek C, Terry J, Senger C, McKinnon ML, Seear M, Prendiville JS, Tucker LB, Houghton K, Cabral DA, Guzman J, Petty RE, Brown KL, Tekano J, Wu J, Morishita KA*, Turvey SE* (2017). The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus. Clin Immunol 175:143-146. PMID: 28043923
^These authors contributed equally to this paper. *Co-senior and co-corresponding authors.
Stiemsma LT, Turvey SE (2017). Asthma and the microbiome: Defining the critical window in early life. Allergy, Asthma Clin Immunol 6;13:3. PMID: 28077917
Marwaha AK, Panagiotopoulos C, Biggs CM, Staiger S, Del Bel KL, Hirschfeld AF, Priatel JJ, Turvey SE, Tan R (2017). Pre-diagnostic genotyping identifies T1D subjects with impaired Treg IL-2 signaling and an elevated proportion of FOXP3+IL-17+ cells. Genes Immun 18(1): 15-21. PMID: 28053319
Stiemsma LT, Arrieta MC, Dimitriu PA, Cheng J, Thorson L, Lefebvre DL, Azad MB, Subbarao P, Mandhane P, Becker A, Sears MR, Kollman TR, Canadian Healthy Infant Longitudinal Development (CHILD) Study Investigators, Mohn WW, Finlay BB, Turvey SE (2016). Shifts in Lachnospira and Clostridium sp. in the 3-month stool microbiome are associated with preschool age asthma. Clin Sci (Lond) 130(23): 2199-2207. PMID: 27634868
Rozmus J, McDonald R, Fung SY, Del Bel KL, Roden J, Senger C, Schultz KR, McKinnon ML, Davis J, Turvey SE (2016). Successful clinical treatment and functional immunological normalization of human MALT1 deficiency following hematopoietic stem cell transplantation. Clin Immunol. 168:1-5. PMID: 27109639
Klein T, Fung SY, Renner F, Blank MA, Dufour A, Kang S, Bolger-Munro M, Scurll JM, Priatel JJ, Schweigler P, Melkko S, Gold MR, Viner RI, Régnier CH, Turvey SE, Overall CM (2015). The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. Nat Commun 6: 8777. PMID: 26525107
Arrieta MC^, Stiemsma LT^, Dimitriu PA, Thorson L, Russell S, Yurist-Doutsch S, Kuzeljevic B, Gold MJ, Lefebvre DL, Subbarao P, Mandhane P, Becker A, McNagny KM, Sears MR, Kollmann T, the CHILD Study Investigators, Mohn, WM, Turvey SE*, Finlay BB* (2015). Early infancy microbial and metabolic alterations impact risk of childhood asthma. Sci Transl Med 7(307):307ra152. ^These authors contributed equally to this paper. *Co-senior and co-corresponding authors. PMID: 26424567
Yang H, Fung SY, Xu S, Sutherland DP, Kollmann TR, Liu M, Turvey SE (2015). Amino Acid-Dependent Attenuation of Toll-like Receptor Signaling by Peptide-Gold Nanoparticle Hybrids. ACS Nano 9(7):6674-6784. PMID: 26083966
McKinnon ML, Rozmus J, Fung SY, Hirschfeld AF, Del Bel KL, Thomas L, Marr N, Martin SD, Marwaha AK, Priatel JJ, Tan R, Senger C, Tsang A, Prendiville J, Junker AK, Seear M, Schultz KR, Sly LM, Holt RA, Patel MS, Friedman JM, Turvey SE (2014). Combined immunodeficiency associated with homozygous MALT1 mutations. J Allergy Clin Immunol 133(5):1458-62,1462.e1-7. PMID: 24332264