Overview

I am a Registered Dietitian with a strong interest in maternal child nutrition and global health. I have worked as a Clinical Dietitian at BC Children's Hospital and internationally with the United Nations (Rwanda, Malawi, Ethiopia, Timor-Leste, Italy, New York) in operations research, humanitarian aid, and nutrition programming. My research is focused on maternal and child nutrition, micronutrient deficincies, hemoglobin and iron status, and inherited blood disorders.

Publications

Comparison of a New Multiplex Immunoassay for Measurement of Ferritin, Soluble Transferrin Receptor, Retinol-Binding Protein, C-Reactive Protein and a-Acid-glycoprotein Concentrations against a Widely-Used s-ELISA Method
Diagnostics
DOI: 10.3390/diagnostics8010013
02/2018

Prevalence of Vitamin D Deficiency Varies Widely by Season in Canadian Children and Adolescents with Sickle Cell Disease
Journal of Clinical Medicine
DOI: 10.3390/jcm7020014
01/2018

Mean hemoglobin concentrations in fasting venous and non-fasting capillary blood of Cambodian women using a hemoglobinometer and an automated hematology analyzer.
Clinical chemistry and laboratory medicine
DOI: 10.1515/cclm-2017-0118
PubMed: 28412720
10/2017

High prevalence of thiamine (vitamin B1) deficiency in early childhood among a nationally representative sample of Cambodian women of childbearing age and their children.
PLoS Neglected Tropical Diseases
DOI: 10.1371/journal.pntd.0005814
PubMed: 28873391
09/2017

Serum Soluble Transferrin Receptor Concentrations Are Elevated in Congolese Children with Glucose-6-Phosphate Dehydrogenase Variants, but Not Sickle Cell Variants or a-Thalassemia.
The Journal of nutrition
DOI: 10.3945/jn.117.252635
PubMed: 28768839
09/2017

The effect of inflammation on serum zinc concentrations and the prevalence estimates of population-level zinc status among Congolese children aged 6-59 months.
European journal of clinical nutrition
DOI: 10.1038/ejcn.2017.127
PubMed: 28832571
08/2017

The effect of oral iron with or without multiple micronutrients on hemoglobin concentration and hemoglobin response among nonpregnant Cambodian women of reproductive age: a 2 x 2 factorial, double-blind, randomized controlled supplementation trial
The American Journal of Clinical Nutrition
Crystal D Karakochuk, Mikaela K Barker, Kyly C Whitfield, Susan I Barr, Suzanne M Vercauteren, Angela M Devlin, Jennifer A Hutcheon, Lisa A Houghton, Sophonneary Prak, Kroeun Hou, Tze Lin Chai, Ame Stormer, Sokhoing Ly, Robyn Devenish, Christian Oberkanins, Helene Pühringer, Kimberly B Harding, Luz M De-Regil, Klaus Kraemer, Tim J Green
DOI: 10.3945/ajcn.116.140996
07/2017

Variation in haemoglobin measurement across different HemoCue devices and device operators in rural Cambodia.
Journal of clinical pathology
DOI: 10.1136/jclinpath-2017-204351
PubMed: 28275044
07/2017

Correlations between Maternal, Breast Milk, and Infant Vitamin B12 Concentrations among Mother–Infant Dyads in Vancouver, Canada and Prey Veng, Cambodia: An Exploratory Analysis
Nutrients
DOI: 10.3390/nu9030270
03/2017

Comparison of four immunoassays to measure serum ferritin concentrations and iron deficiency prevalence among non-pregnant Cambodian women and Congolese children
Clinical Chemistry and Laboratory Medicine
Karakochuk, C.D. and Whitfield, K.C. and Rappaport, A.I. and Barr, S.I. and Vercauteren, S.M. and McLean, J. and Hou, K. and Talukder, A. and Houghton, L.A. and Bailey, K.B. and Boy, E. and Green, T.J.
DOI: 10.1515/cclm-2016-0421
2017

Household Consumption of Thiamin-Fortified Fish Sauce Increases Erythrocyte Thiamin Concentrations among Rural Cambodian Women and Their Children Younger Than 5 Years of Age: A Randomized Controlled Efficacy Trial
Journal of Pediatrics
Whitfield, K.C. and Karakochuk, C.D. and Kroeun, H. and Sokhoing, L. and Chan, B.B. and Borath, M. and Sophonneary, P. and Moore, K. and Tong, J.K.T. and McLean, J. and Talukder, A. and Lynd, L.D. and Li-Chan, E.C.Y. and Kitts, D.D. and Green, T.J.
DOI: 10.1016/j.jpeds.2016.10.066
2016

Perinatal consumption of thiamine-fortified fish sauce in rural Cambodia: A randomized clinical trial
JAMA Pediatrics
Whitfield, K.C. and Karakochuk, C.D. and Kroeun, H. and Hampel, D. and Sokhoing, L. and Chan, B.B. and Borath, M. and Sophonneary, P. and McLean, J. and Talukder, A. and Lynd, L.D. and Li-Chan, E.C.Y. and Kitts, D.D. and Allen, L.H. and Green, T.J.
DOI: 10.1001/jamapediatrics.2016.2065
2016

Improved sanitation facilities are associated with higher body mass index and higher hemoglobin concentration among rural cambodian women in the first trimester of pregnancy
American Journal of Tropical Medicine and Hygiene
Janmohamed, A. and Karakochuk, C.D. and McLean, J. and Green, T.J.
DOI: 10.4269/ajtmh.16-0278
2016

A method comparison study between two hemoglobinometer models (Hemocue Hb 301 and Hb 201+) to measure hemoglobin concentrations and estimate anemia prevalence among women in Preah Vihear, Cambodia
International Journal of Laboratory Hematology
Rappaport, A.I. and Karakochuk, C.D. and Whitfield, K.C. and Kheang, K.M. and Green, T.J.
DOI: 10.1111/ijlh.12583
2016

Prenatal supplementation with Corn Soya Blend Plus reduces the risk of maternal anemia in late gestation and lowers the rate of preterm birth but does not significantly improve maternal weight gain and birth anthropometric measurements in rural Cambodian women: A randomized trial
American Journal of Clinical Nutrition
Janmohamed, A. and Karakochuk, C.D. and Boungnasiri, S. and Chapman, G.E. and Janssen, P.A. and Brant, R. and Green, T.J. and McLean, J.
DOI: 10.3945/ajcn.114.104034
2016

Folic acid fortified milk increases blood folate to concentrations associated with a very low risk of neural tube defects in Singaporean women of childbearing age
Asia Pacific Journal of Clinical Nutrition
Cheong, M. and Xiao, H.Y. and Tay, V. and Karakochuk, C.D. and Liu, Y.A. and Harvey, S. and Lamers, Y. and Houghton, L.A. and Kitts, D.D. and Green, T.J.
DOI: 10.6133/apjcn.2016.25.1.08
2016

Median urinary iodine concentrations are indicative of adequate iodine status among women of reproductive age in prey veng, Cambodia
Nutrients
Karakochuk, C.D. and Michaux, K.D. and Chai, T.L. and Chan, B.B. and Whit?eld, K.C. and Barr, S.I. and McLean, J. and Talukder, A. and Hou, K. and Ly, S. and Green, T.J.
DOI: 10.3390/nu8030139
2016

Anemia and micronutrient status ofwomen of childbearing age and children 6–59 months in the Democratic Republic of the Congo
Nutrients
Harvey-Leeson, S. and Karakochuk, C.D. and Hawes, M. and Tugirimana, P.L. and Bahizire, E. and Akilimali, P.Z. and Michaux, K.D. and Lynd, L.D. and Whitfield, K.C. and Moursi, M. and Boy, E. and Foley, J. and McLean, J. and Houghton, L.A. and Gibson, R.S. and Green, T.J.
DOI: 10.3390/nu8020098
2016

Anthropometric measures are simple and accurate paediatric weight-prediction proxies in resource-poor settings with a high HIV prevalence
Archives of Disease in Childhood
Whitfield, K.C. and Wozniak, R. and Pradinuk, M. and Karakochuk, C.D. and Anabwani, G. and Daly, Z. and MacLeod, S.M. and Larson, C.P. and Green, T.J.
DOI: 10.1136/archdischild-2015-309645
2016

Factors affecting the acceptability and consumption of Corn Soya Blend Plus as a prenatal dietary supplement among pregnant women in rural Cambodia
Public Health Nutrition
Janmohamed, A. and Karakochuk, C.D. and Boungnasiri, S. and Whitfield, K.C. and Chapman, G.E. and Janssen, P. and McLean, J. and Green, T.J.
DOI: 10.1017/S1368980015003018
2016

The homozygous hemoglobin EE genotype and chronic inflammation are associated with high serum ferritin and soluble transferrin receptor concentrations among women in rural Cambodia
Journal of Nutrition
Karakochuk, C.D. and Whitfield, K.C. and Rappaport, A.I. and Barr, S.I. and Vercauteren, S.M. and McLean, J. and Prak, S. and Hou, K. and Talukder, A. and Devenish, R. and Green, T.J.
DOI: 10.3945/jn.115.218636
2015

Food Sharing Practices in Households Receiving Supplemental Foods for the Treatment of Moderate Acute Malnutrition in Ethiopian Children
Journal of Hunger and Environmental Nutrition
Karakochuk, C.D. and van den Briel, T. and Stephens, D. and Zlotkin, S.
DOI: 10.1080/19320248.2014.962772
2015

Elevated levels of iron in groundwater in Prey Veng province in Cambodia: A possible factor contributing to high iron stores in women
Journal of Water and Health
Karakochuk, C.D. and Murphy, H.M. and Whitfield, K.C. and Barr, S.I. and Vercauteren, S.M. and Talukder, A. and Porter, K. and Kroeun, H. and Eath, M. and McLean, J. and Green, T.J.
DOI: 10.2166/wh.2014.297
2015

Poor thiamin and riboflavin status is common among women of childbearing age in rural and urban Cambodia
Journal of Nutrition
Whitfield, K.C. and Karakochuk, C.D. and Liu, Y. and McCann, A. and Talukder, A. and Kroeun, H. and Ward, M. and McNulty, H. and Lynd, L.D. and Kitts, D.D. and Li-Chan, E.C.Y. and McLean, J. and Green, T.J.
DOI: 10.3945/jn.114.203604
2015

Maternal vitamin D3 supplementation at 50 mg/d protects against low serum 25-hydroxyvitamin D in infants at 8 wk of age: A randomized controlled trial of 3 doses of vitamin D beginning in gestation and continued in lactation
American Journal of Clinical Nutrition
March, K.M. and Chen, N.N. and Karakochuk, C.D. and Shand, A.W. and Innis, S.M. and Von Dadelszen, P. and Barr, S.I. and Lyon, M.R. and Whiting, S.J. and Weiler, H.A. and Green, T.J.
DOI: 10.3945/ajcn.114.106385
2015

Evaluation of two methods to measure hemoglobin concentration among women with genetic hemoglobin disorders in Cambodia: A method-comparison study
Clinica Chimica Acta
Karakochuk, C.D. and Janmohamed, A. and Whitfield, K.C. and Barr, S.I. and Vercauteren, S.M. and Kroeun, H. and Talukder, A. and McLean, J. and Green, T.J.
DOI: 10.1016/j.cca.2014.12.021
2015

Genetic hemoglobin disorders rather than iron deficiency are a major predictor of hemoglobin concentration in women of reproductive age in rural prey veng, Cambodia
Journal of Nutrition
Karakochuk, C.D. and Whitfield, K.C. and Barr, S.I. and Lamers, Y. and Devlin, A.M. and Vercauteren, S.M. and Kroeun, H. and Talukder, A. and McLean, J. and Green, T.J.
DOI: 10.3945/jn.114.198945
2015

Treatment of moderate acute malnutrition with ready-to-use supplementary food results in higher overall recovery rates compared with a corn-soya blend in children in southern Ethiopia: An operations research trial
American Journal of Clinical Nutrition
Karakochuk, C. and Van Den Briel, T. and Stephens, D. and Zlotkin, S.
DOI: 10.3945/ajcn.111.029744
2012

Research

Current projects
Is iron deficiency a cause of anemia in non-pregnant Cambodian women of reproductive age? A 2x2 randomized controlled supplementation trial to investigate the hemoglobin response to iron supplementation, with or without multiple micronutrients.

Prevalence of sickle cell hemoglobin variants and glucose-6-phosphate dehydrogenase deficiency among Congolese children and associations with hemoglobin and iron biomarkers. A cross-sectional survey of n=730 children 6-59 months of age in two provinces in the Democratic Republic of the Congo.

Grants

Canadian Institutes of Health Research – Open Operating Grant Awarded: $233,428 CAD

Sight and Life (Dr. Klaus Kraemer) Awarded: $50,000 USD

Co-Investigator. Is iron deficiency the cause of anemia among women of reproductive age in Cambodia? A 2 x 2 factorial randomized controlled trial of oral iron and multiple micronutrient supplementation.

Honours & Awards

2015, Emerging Leaders in Nutrition Science Poster Competition Award, sponsored by the Global Nutrition Council of the American Society of Nutrition

2016, Outstanding Achievements for a Doctoral Candidate Award, BC Children’s Hospital Research Institute, Vancouver, Canada.

2016, Early Career Award for Contribution to Alleviation of Micronutrient Malnutrition International Life Sciences Institute.

Research Group Members

Mikaela Barker, Volunteer
Cara Mayer, Work Learn Student
Shannon Steele, Graduate Student
Kaitlyn Samson