Overview

My current practice is based on the diagnosis and study of neoplastic and non-neoplastic diseases in children. My main interest is in pediatric solid tumors, gastrointestinal and liver pathology, and sudden infant death pathology.

Publications

Vasoactive Intestinal Polypeptide Promotes Intestinal Barrier Homeostasis and Protection Against Colitis in Mice
PLOS ONE
Xiujuan Wu, Victoria S. Conlin, Vijay Morampudi, Natasha R. Ryz, Yasmin Nasser, Ganive Bhinder, Kirk S. Bergstrom, Hong B. Yu, Chris C. M. Waterhouse, Allison M. J. Buchan, Oana E. Popescu, William T. Gibson, James A. Waschek, Bruce A. Vallance, Kevan Jacobson
DOI: 10.1371/journal.pone.0125225
05/2015

Prenatal and postnatal findings in serpentine fibula polycystic kidney syndrome and a review of the NOTCH2 spectrum disorders
American Journal of Medical Genetics Part A
Brett M. Martin, Margarita H. Ivanova, Anna Sarukhanov, Ashley Kim, Patricia Power, Denise Pugash, Oana-Eugenia Popescu, Ralph S. Lachman, Deborah Krakow, Millan S. Patel
DOI: 10.1002/ajmg.a.36656
07/2014

ChildSeq-RNA
The Journal of Molecular Diagnostics
Mohammed A. Qadir, Shing H. Zhan, Brian Kwok, Jeremy Bruestle, Becky Drees, Oana-Eugenia Popescu, Poul H. Sorensen
DOI: 10.1016/j.jmoldx.2014.01.002
05/2014

New anomalies due to methotrexate and misoprostol exposure in early pregnancy
International Journal of Gynecology & Obstetrics
Kate MacDonald, Wendy V. Norman, Oana Popescu
DOI: 10.1016/j.ijgo.2013.03.026
06/2013

Fetal Progeria: Prenatal Sonographic Findings in Petty Syndrome
Journal of Ultrasound in Medicine
D. Pugash, K. A. Schrader, C. P. Dunham, O.-E. Popescu, M. A. Sargent, A. M. Lehman, S. L. Yong, L. A. Clarke
DOI: 10.7863/ultra.32.5.881
04/2013

Carnitine Palmitoyltransferase I and Sudden Unexpected Infant Death in British Columbia First Nations
PEDIATRICS
G. B. Sinclair, S. Collins, O. Popescu, D. McFadden, L. Arbour, H. D. Vallance
DOI: 10.1542/peds.2011-2924
10/2012

SHIP-Deficient Mice Develop Spontaneous Intestinal Inflammation and Arginase-Dependent Fibrosis
The American Journal of Pathology
Keith W. McLarren, Alexandra E. Cole, Shelley B. Weisser, Nicole S. Voglmaier, Victoria S. Conlin, Kevan Jacobson, Oana Popescu, Jean-Luc Boucher, Laura M. Sly
DOI: 10.1016/j.ajpath.2011.03.018
07/2011

The spectrum of eosinophilic cystitis in males: case series and literature review
Archives of Pathology & Laboratory Medicine
DOI: 10.1043/1543-2165-133.2.289
PubMed: 19195972
02/2009

Noninvasive sacral chordoma presenting as a benign soft tissue mass
Annals of Diagnostic Pathology
Oana-Eugenia Baboiu, William M. Taylor
DOI: 10.1016/j.anndiagpath.2005.11.003
04/2006

Hepatic Mesenchymal Hamartoma: Cytogenetic Analysis of a Case and Review of the Literature
Pediatric and Developmental Pathology
Oana-Eugenia Baboiu, Howard Saal, Margaret Collins
DOI: 10.2350/07-02-0225
2006

Research

Current Projects
The project I am working now is about liver and renal histopathology in sudden infant death cases in aboriginal children homozygous for CPT1AP479L mutation. This mutation is associated with recurrent attacks of hypoketotic hypoglycemia during fasting, fever, and intercurrent illnesses. Clinical presentation of CPT1A deficiency is variable and ranges from sudden death in infancy to liver disease with hepatomegaly later in life. It appears to have specific histological findings in sudden death cases of homozygous infants homozygous for CPT1AP479L mutation compared with heterozygous and wild type cases.