TAKE-IT TOO builds on the TAKE-IT study, which combined an electronic pillbox with medication adherence feedback to patients via text message, and a trained study coach to help participants identify and address barriers to medication adherence. TAKE-IT TOO will adapt the TAKE-IT intervention into clinical practice and aims to develop a better e-pillbox and companion website for real-world use.
A pilot clinical trial to evaluate the feasibility and acceptability of: A prospective, unblinded, randomized-controlled, multicenter biomarker intervention trial of a urinary CXCL10 clinical surveillance program in pediatric kidney transplant recipients for early ascertainment and treatment of subclinical allograft inflammation and preservation of kidney transplant function (PROACT Trial)
Pediatric solid organ transplant (SOT) recipients are at an increased risk of infection because of the need for life-long immunosuppression. Vaccine recommendations and schedules for pediatric SOT recipients differ widely from those for immunocompetent children and adolescents, and these guidelines change with new evidence and new vaccines.