A Prospective study Evaluating COVID-19 Vaccine immunogenicity in Organ Transplant Recipients (the PREVenT-COVID study) Extension– Pediatric Arm

Project Summary

Children who received organ transplant are eligible to receive COVID-19 vaccine when it is licensed for their age group. People with organ transplant may have different immune response to COVID-19 vaccine compared to their "healthy" peers. This is the extension of the PREVenT-COVID study. We will assess immune response to COVID-19 vaccine in BC children living with organ transplant 2 years following their first vaccination to better understand long-term immunity.  

This project is supported by the Transplant Research Foundation of British Columbia and Big Gifts for Little Lives Alberta.

Project Status

Status: Active, data collection ongoing
Study Start Date: April 8, 2022
Study End Date: December 31, 2024

Study Enrollment Status: Closed
Start Date: Oct 1, 2022
End Date: July 24, 2023

Project Team

Principal Investigator

Dr. Hana Mitchell

Co-investigators

Catherine Burton, Assistant Professor, Department of Pediatrics, University of Alberta
Sneha Suresh, Associate Professor, Department of Pediatrics, University of Alberta
Manish Sadarangani, Associate Professor, Department of Pediatrics, Faculty of Medicine, University of British Columbia
Tom Blydt-Hansen, Associate Professor, Department of Pediatrics, Faculty of Medicine, University of British Columbia

Research Team Members

Candice Wiedman, Research Assistant
Kimia Navirian, Research Assistant
Monica Ho, Research Coordinator

Enrollment Eligibility Criteria
  1. Have been enrolled in PREVent-COVID study
  2. At BCCH, potential participants who are SOT recipients must also have previously consented to the BCCH Biobanking Registry (H17-06240) in order to be eligible OR are willing to consent into the BCCH Biobanking Registry at the time of enrolling into this current study.
  3. At BCCH, potential participants have to be able to come to BCCH for all the study-related blood draws

For more information, please email Candice.Wiedman@bcchr.ca.